Pinealon

Pinealon

Pinealon is a synthetic tripeptide (Glu-Asp-Arg) developed as part of the peptide bioregulator research programme at the St. Petersburg Institute of Bioregulation and Gerontology, under the direction of Professor Vladimir Khavinson. It is classified as a pineal gland peptide bioregulator, designed to investigate the role of the pineal gland in circadian rhythm regulation, neuroprotection, and age-related neurological decline. Pinealon has been studied in preclinical models for its potential effects on neuronal survival, antioxidant defence, and melatonin-related signalling pathways.

Mechanism of Action

Pinealon is hypothesised to act as a gene expression modulator, interacting with chromatin in pinealocytes and neuronal cells to regulate transcription of genes associated with antioxidant defence, circadian rhythm maintenance, and neuronal survival. Preclinical studies have demonstrated effects on superoxide dismutase (SOD) and catalase activity, suggesting a role in attenuating oxidative stress in neuronal tissue. Pinealon has also been investigated for its influence on melatonin synthesis pathways and its potential neuroprotective effects in models of ischaemia and age-related neurodegeneration.

Research Applications

• Pineal gland biology and circadian rhythm regulation studies
• Neuronal antioxidant defence and oxidative stress research
• Melatonin synthesis pathway and pinealocyte function investigation
• Neuroprotection and age-related neurodegeneration preclinical models
• Peptide bioregulator epigenetic mechanism research

Specifications

• Molecular Formula: C₁₄H₂₂N₄O₇
• Molecular Weight: 358.35 g/mol
• CAS Number: 418163-08-3
• Purity: ≥98%
• Form: Lyophilised powder
• Storage: -20°C
• Shelf Life: 24 months

Note: Verify concentration and identity before use in experimental protocols.

This product is intended for legitimate laboratory and analytical research use only. Not for diagnostic, therapeutic, or consumer use.