Lipo-B LC216

Lipo-B LC216

Lipo-B LC216 is a research-grade lipotropic compound formulation combining B-vitamin cofactors with L-carnitine at a standardised concentration of 216 mg per 10 mL, designed for laboratory investigation of lipid metabolism, mitochondrial fatty acid transport, and hepatic lipotropic mechanisms. The LC216 designation reflects the L-carnitine content of the formulation, which is combined with the classic Lipo-B lipotropic matrix (methionine, inositol, choline, and cyanocobalamin) to provide a more comprehensive tool for studying the intersection of carnitine-dependent fatty acid oxidation and one-carbon metabolism in preclinical research models.

Mechanism of Action

Lipo-B LC216 combines the lipotropic activity of the B-vitamin matrix with the mitochondrial fatty acid transport function of L-carnitine. L-carnitine is an essential cofactor for the carnitine palmitoyltransferase (CPT1/CPT2) shuttle system, which transports long-chain fatty acyl-CoA esters across the inner mitochondrial membrane for β-oxidation. Without adequate carnitine, long-chain fatty acids cannot enter the mitochondrial matrix for oxidation, leading to cytoplasmic lipid accumulation. The Lipo-B components (methionine, inositol, choline, cyanocobalamin) support hepatic phospholipid synthesis, VLDL assembly, and one-carbon methylation, complementing the carnitine-mediated fatty acid oxidation pathway. Together, this formulation supports investigation of synergistic lipotropic and mitochondrial mechanisms in hepatic steatosis, obesity, and metabolic disease research.

Research Applications

• L-carnitine-dependent mitochondrial fatty acid transport and β-oxidation studies
• CPT1/CPT2 shuttle system and carnitine metabolism research
• Hepatic lipid metabolism, VLDL assembly, and steatosis prevention models
• One-carbon metabolism, methylation, and phospholipid synthesis investigation
• Obesity, metabolic syndrome, and lipotropic mechanism research

Specifications

• Molecular Formula: Lipotropic blend with L-carnitine (216 mg/10 mL)
• Molecular Weight: N/A (multi-component)
• CAS Number: N/A (blend)
• Purity: ≥98%
• Form: Lyophilised powder
• Storage: -20°C
• Shelf Life: 24 months

This product is intended for legitimate laboratory and analytical research use only. Not for diagnostic, therapeutic, or consumer use.