AOD9604

AOD9604

AOD9604 is a synthetic peptide fragment derived from the C-terminus of human growth hormone (hGH), specifically residues 176–191, with a tyrosine residue added at the N-terminus. Unlike full-length hGH, AOD9604 does not stimulate IGF-1 production or promote cell proliferation, making it a selective research tool for studying the lipolytic properties of growth hormone independent of its anabolic effects.

Mechanism of Action

AOD9604 has been studied in preclinical models for its effects on adipose tissue lipolysis and lipogenesis inhibition via interaction with β-adrenergic receptors and downstream cAMP signalling pathways, without binding to the GH receptor or activating the JAK-STAT pathway. This selectivity makes it a useful tool for studying the dissociation of lipolytic and growth-promoting effects of GH in preclinical models.

Research Applications

• Adipose tissue lipolysis and lipid metabolism studies
• Adipocyte lipid metabolism and differentiation studies
• Growth hormone fragment biology research
• Adipose tissue signalling and β-adrenergic receptor studies
• Lipid metabolism and energy homeostasis pathway studies

Specifications

• Molecular Formula: C₇₈H₁₂₃N₂₃O₂₃S₂
• Molecular Weight: 1815.1 g/mol
• CAS Number: 221231-10-3
• Purity: ≥98%
• Form: Lyophilised powder
• Storage: -20°C
• Shelf Life: 24 months

This product is intended for legitimate laboratory and analytical research use only. Not for human use, veterinary use, or consumer use. Not for diagnostic or therapeutic purposes.