Lipo-B

Lipo-B

Lipo-B is a research-grade lipotropic B-vitamin compound formulation designed for laboratory investigation of hepatic lipid metabolism, one-carbon metabolism, and lipotropic mechanisms. The Lipo-B formulation combines methionine, inositol, choline, and cyanocobalamin (Vitamin B12) — the classical lipotropic quartet — each contributing distinct and complementary roles in hepatic fat mobilisation, phospholipid synthesis, and methylation biochemistry. This formulation serves as the foundational lipotropic matrix used in research investigating the prevention of hepatic steatosis and the regulation of lipid transport in preclinical models.

Mechanism of Action

Each component of Lipo-B contributes to hepatic lipid homeostasis through distinct biochemical pathways. Methionine is an essential amino acid that donates methyl groups via S-adenosylmethionine (SAM) to support phosphatidylcholine synthesis and hepatic methylation reactions critical for VLDL assembly and export. Inositol is a structural component of phosphatidylinositol, a key membrane phospholipid involved in lipid signalling and hepatic fat export. Choline is the direct precursor to phosphatidylcholine and acetylcholine, and is essential for VLDL particle formation — the primary mechanism by which the liver exports triglycerides to peripheral tissues. Cyanocobalamin (Vitamin B12) supports methionine synthase in the folate-methionine cycle, maintaining the methylation capacity required for phospholipid synthesis. Together, these components promote hepatic triglyceride export, reduce lipid accumulation, and support fatty acid oxidation in preclinical research models.

Research Applications

• Hepatic lipid metabolism, VLDL assembly, and triglyceride export studies
• One-carbon metabolism, SAM pathway, and methylation research
• Non-alcoholic fatty liver disease (NAFLD) and hepatic steatosis preclinical models
• Phospholipid synthesis, choline metabolism, and membrane biology investigation
• Lipotropic mechanism and B-vitamin cofactor research

Specifications

• Molecular Formula: Lipotropic blend (methionine, inositol, choline, cyanocobalamin)
• Molecular Weight: N/A (multi-component)
• CAS Number: N/A (blend)
• Purity: ≥98%
• Form: Lyophilised powder
• Storage: -20°C
• Shelf Life: 24 months

This product is intended for legitimate laboratory and analytical research use only. Not for diagnostic, therapeutic, or consumer use.