{"product_id":"tesamorelin","title":"Tesamorelin","description":"\u003ch2\u003eTesamorelin\u003c\/h2\u003e\n\u003cp\u003eTesamorelin is a synthetic analogue of growth hormone-releasing hormone (GHRH), comprising the full 44-amino acid sequence of endogenous GHRH with a trans-3-hexenoic acid modification at the N-terminus to enhance stability. It is a well-characterised GHRH receptor agonist that has been extensively studied in the context of growth hormone secretion, body composition, and metabolic regulation. Tesamorelin is supplied here as a lyophilised research compound for in vitro and preclinical investigation.\u003c\/p\u003e\n\u003ch3\u003eMechanism of Action\u003c\/h3\u003e\n\u003cp\u003eTesamorelin binds to and activates the GHRH receptor (GHRHR) on somatotroph cells of the anterior pituitary, stimulating the pulsatile release of endogenous growth hormone (GH). The resulting GH elevation promotes hepatic IGF-1 synthesis, which mediates downstream anabolic and lipolytic effects. Unlike exogenous GH administration, tesamorelin preserves the physiological pulsatility of GH secretion and operates within the feedback regulation of the somatotropic axis, making it a valuable tool for studying GHRH receptor pharmacology and GH-IGF-1 axis dynamics.\u003c\/p\u003e\n\u003ch3\u003eResearch Applications\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003eGHRH receptor pharmacology and pituitary somatotroph function studies\u003c\/li\u003e\n\u003cli\u003eGrowth hormone secretion and pulsatility modelling\u003c\/li\u003e\n\u003cli\u003eIGF-1 axis regulation and downstream signalling research\u003c\/li\u003e\n\u003cli\u003eVisceral adipose tissue metabolism and lipolysis investigation\u003c\/li\u003e\n\u003cli\u003eBody composition and metabolic syndrome preclinical models\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3\u003eSpecifications\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eMolecular Formula:\u003c\/strong\u003e \u003cmeta charset=\"utf-8\"\u003eC₂₂₁H₃₆₆N₇₂O₆₇S\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eMolecular Weight:\u003c\/strong\u003e \u003cmeta charset=\"utf-8\"\u003e5135.89 g\/mol\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eCAS Number:\u003c\/strong\u003e 218949-48-5\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003ePurity:\u003c\/strong\u003e ≥98%\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eForm:\u003c\/strong\u003e Lyophilised powder\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eStorage:\u003c\/strong\u003e -20°C\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eShelf Life:\u003c\/strong\u003e 24 months\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cem\u003eThis product is intended for legitimate laboratory and analytical research use only. Not for diagnostic, therapeutic, or consumer use.\u003c\/em\u003e\u003c\/p\u003e","brand":"Vanta Labs","offers":[{"title":"2mg","offer_id":58103431856392,"sku":"TESA-2MG","price":27.9,"currency_code":"GBP","in_stock":true},{"title":"5mg","offer_id":58103431889160,"sku":"TESA-5MG","price":27.9,"currency_code":"GBP","in_stock":true},{"title":"10mg","offer_id":58103431921928,"sku":"TESA-10MG","price":50.99,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1049\/8886\/8872\/files\/tesamorelin.png?v=1782893484","url":"https:\/\/vantalabsuk.com\/products\/tesamorelin","provider":"Vanta Labs","version":"1.0","type":"link"}