{"product_id":"tb-500","title":"TB-500","description":"\u003ch2\u003eTB-500 (Thymosin Beta-4)\u003c\/h2\u003e\n\u003cp\u003eTB-500 is a synthetic peptide fragment corresponding to the active region of Thymosin Beta-4 (Tβ4), a ubiquitous 43-amino acid protein found in virtually all nucleated mammalian cells. Tβ4 is one of the most abundant intracellular peptides in the body and plays a central role in actin sequestration, cytoskeletal organisation, and cell migration. TB-500 has been extensively studied in preclinical models for its roles in tissue repair, angiogenesis, and inflammation modulation, making it a widely used research tool in regenerative biology.\u003c\/p\u003e\n\u003ch3\u003eMechanism of Action\u003c\/h3\u003e\n\u003cp\u003eTB-500 exerts its biological effects primarily through binding to G-actin monomers via its LKKTETQ actin-binding domain, thereby regulating actin polymerisation and cytoskeletal dynamics. This interaction promotes cell migration and proliferation in endothelial cells, keratinocytes, and myocytes. Additionally, TB-500 has been shown to upregulate matrix metalloproteinases (MMPs), stimulate angiogenesis via VEGF-dependent pathways, and modulate inflammatory cytokine profiles — collectively supporting its investigation in wound healing and tissue regeneration models.\u003c\/p\u003e\n\u003ch3\u003eResearch Applications\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003eActin dynamics, cytoskeletal organisation, and cell migration studies\u003c\/li\u003e\n\u003cli\u003eWound healing and tissue regeneration preclinical models\u003c\/li\u003e\n\u003cli\u003eAngiogenesis and endothelial cell proliferation research\u003c\/li\u003e\n\u003cli\u003eCardiac and skeletal muscle repair investigation\u003c\/li\u003e\n\u003cli\u003eInflammation modulation and anti-fibrotic research\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3\u003eSpecifications\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eMolecular Formula:\u003c\/strong\u003e \u003cmeta charset=\"utf-8\"\u003eC₂₁₂H₃₅₀N₅₆O₇₈S\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eMolecular Weight:\u003c\/strong\u003e 4963.5 g\/mol\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eCAS Number:\u003c\/strong\u003e 77591-33-4\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003ePurity:\u003c\/strong\u003e ≥98%\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eForm:\u003c\/strong\u003e Lyophilised powder\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eStorage:\u003c\/strong\u003e -20°C\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eShelf Life:\u003c\/strong\u003e 24 months\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cem\u003eThis product is intended for legitimate laboratory and analytical research use only. Not for diagnostic, therapeutic, or consumer use.\u003c\/em\u003e\u003c\/p\u003e","brand":"Vanta Labs","offers":[{"title":"5mg","offer_id":58103431790856,"sku":"TB500-5MG","price":18.35,"currency_code":"GBP","in_stock":true},{"title":"10mg","offer_id":58103431823624,"sku":"TB500-10MG","price":28.99,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1049\/8886\/8872\/files\/tb-500.png?v=1782893614","url":"https:\/\/vantalabsuk.com\/products\/tb-500","provider":"Vanta Labs","version":"1.0","type":"link"}