{"product_id":"survodutide","title":"Survodutide","description":"\u003ch2\u003eSurvodutide\u003c\/h2\u003e\n\u003cp\u003eSurvodutide is a synthetic dual agonist peptide targeting both the glucagon receptor (GCGR) and the glucagon-like peptide-1 receptor (GLP-1R). It represents a next-generation approach to metabolic research beyond single-receptor GLP-1 agonism, combining the complementary metabolic actions of glucagon and GLP-1 signalling pathways. Survodutide has attracted significant preclinical and clinical research interest for its potential effects on energy expenditure, hepatic lipid metabolism, and body weight regulation.\u003c\/p\u003e\n\u003ch3\u003eMechanism of Action\u003c\/h3\u003e\n\u003cp\u003eSurvodutide co-activates GLP-1R and GCGR, both G-protein-coupled receptors that signal through cAMP elevation. GLP-1R activation enhances glucose-dependent insulin secretion and suppresses appetite via central and peripheral mechanisms, while GCGR activation stimulates hepatic glucose output, promotes lipolysis, and increases energy expenditure through thermogenic pathways. The dual agonism is hypothesised to produce additive or synergistic effects on fat oxidation and weight reduction, making survodutide a valuable tool for studying GCGR\/GLP-1R crosstalk and metabolic regulation.\u003c\/p\u003e\n\u003ch3\u003eResearch Applications\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003eDual GCGR\/GLP-1R pharmacology and receptor crosstalk studies\u003c\/li\u003e\n\u003cli\u003eHepatic lipid metabolism and non-alcoholic fatty liver disease (NAFLD) models\u003c\/li\u003e\n\u003cli\u003eEnergy expenditure and thermogenesis research\u003c\/li\u003e\n\u003cli\u003eObesity and body composition preclinical investigation\u003c\/li\u003e\n\u003cli\u003eInsulin secretion and glucose homeostasis modelling\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3\u003eSpecifications\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eMolecular Formula:\u003c\/strong\u003e \u003cmeta charset=\"utf-8\"\u003e \u003cspan class=\"T286Pc\" data-sfc-cp=\"\" data-sfc-root=\"ep\" data-sfc-cb=\"\" data-complete=\"true\" data-copy-service-computed-style='font-family: \"Google Sans\", Arial, sans-serif; font-size: 16px; font-weight: 400; margin: 0px; text-decoration: none; border-bottom: 0px rgb(230, 232, 240);'\u003eC₁₉₂H₂₈₉N₄₇O₆₁\u003c!--TgQPHd||[]--\u003e\u003c\/span\u003e\u003cspan data-copy-service-computed-style='font-family: \"Google Sans\", Arial, sans-serif; font-size: 16px; font-weight: 400; margin: 0px; text-decoration: none; border-bottom: 0px rgb(230, 232, 240);'\u003e\u003c!--TgQPHd||[]--\u003e\u003c\/span\u003e\u003c!--TgQPHd||[]--\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eMolecular Weight:\u003c\/strong\u003e \u003cmeta charset=\"utf-8\"\u003e4231.69 g\/mol\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eCAS Number:\u003c\/strong\u003e \u003cmeta charset=\"utf-8\"\u003e2805997-46-8\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003ePurity:\u003c\/strong\u003e ≥98%\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eForm:\u003c\/strong\u003e Lyophilised powder\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eStorage:\u003c\/strong\u003e -20°C\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eShelf Life:\u003c\/strong\u003e 24 months\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cem\u003eThis product is intended for legitimate laboratory and analytical research use only. Not for diagnostic, therapeutic, or consumer use.\u003c\/em\u003e\u003c\/p\u003e","brand":"Vanta Labs","offers":[{"title":"2mg","offer_id":58103431659784,"sku":"SURVO-2MG","price":32.99,"currency_code":"GBP","in_stock":true},{"title":"5mg","offer_id":58103431692552,"sku":"SURVO-5MG","price":60.99,"currency_code":"GBP","in_stock":true},{"title":"10mg","offer_id":58103431725320,"sku":"SURVO-10MG","price":89.99,"currency_code":"GBP","in_stock":true},{"title":"15mg","offer_id":58103431758088,"sku":"SURVO-15MG","price":140.99,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1049\/8886\/8872\/files\/survodutide.png?v=1782893801","url":"https:\/\/vantalabsuk.com\/products\/survodutide","provider":"Vanta Labs","version":"1.0","type":"link"}