{"product_id":"ss-31","title":"SS-31 (Elamipretide)","description":"\u003ch2\u003eSS-31 (Elamipretide)\u003c\/h2\u003e\n\u003cp\u003eSS-31, also known as Elamipretide or MTP-131, is a synthetic tetrapeptide (D-Arg-2’,6’-Dmt-Lys-Phe-NH2) belonging to the Szeto-Schiller (SS) peptide family. It is specifically designed to target and concentrate within the inner mitochondrial membrane, where it interacts with cardiolipin — a phospholipid critical for mitochondrial cristae architecture and electron transport chain function. SS-31 has emerged as a leading research tool in mitochondrial biology, with a substantial body of preclinical literature supporting its investigation across ageing, ischaemia-reperfusion injury, and metabolic disease models.\u003c\/p\u003e\n\u003ch3\u003eMechanism of Action\u003c\/h3\u003e\n\u003cp\u003eSS-31 selectively partitions into the inner mitochondrial membrane due to its alternating aromatic and cationic residues, achieving mitochondrial concentrations several hundred-fold above cytoplasmic levels. It binds directly to cardiolipin, stabilising cristae morphology and preserving the structural integrity of electron transport chain supercomplexes (respirasomes). This interaction reduces mitochondrial reactive oxygen species (ROS) production, restores ATP synthesis efficiency, and inhibits cytochrome c peroxidase activity — collectively attenuating mitochondrial dysfunction and apoptotic signalling.\u003c\/p\u003e\n\u003ch3\u003eResearch Applications\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003eMitochondrial membrane dynamics and cardiolipin interaction studies\u003c\/li\u003e\n\u003cli\u003eElectron transport chain supercomplex stability and bioenergetics research\u003c\/li\u003e\n\u003cli\u003eIschaemia-reperfusion injury and cardiac protection models\u003c\/li\u003e\n\u003cli\u003eMitochondrial ROS production and oxidative stress investigation\u003c\/li\u003e\n\u003cli\u003eAgeing, sarcopenia, and metabolic disease preclinical models\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3\u003eSpecifications\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eMolecular Formula:\u003c\/strong\u003e \u003cmeta charset=\"utf-8\"\u003eC₃₂H₄₉N₉O₅\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eMolecular Weight:\u003c\/strong\u003e 639.8 g\/mol\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eCAS Number:\u003c\/strong\u003e 736992-21-5\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003ePurity:\u003c\/strong\u003e ≥98%\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eForm:\u003c\/strong\u003e Lyophilised powder\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eStorage:\u003c\/strong\u003e -20°C\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eShelf Life:\u003c\/strong\u003e 24 months\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cem\u003eThis product is intended for legitimate laboratory and analytical research use only. Not for diagnostic, therapeutic, or consumer use.\u003c\/em\u003e\u003c\/p\u003e","brand":"Vanta Labs","offers":[{"title":"10mg","offer_id":58103431594248,"sku":"SS31-10MG","price":28.99,"currency_code":"GBP","in_stock":true},{"title":"50mg","offer_id":58103431627016,"sku":"SS31-50MG","price":110.99,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1049\/8886\/8872\/files\/ss-31-elamipretide.png?v=1782893972","url":"https:\/\/vantalabsuk.com\/products\/ss-31","provider":"Vanta Labs","version":"1.0","type":"link"}