{"product_id":"snap-8","title":"Snap-8","description":"\u003ch2\u003eSnap-8\u003c\/h2\u003e\n\u003cp\u003eSnap-8 (Acetyl Glutamyl Octapeptide-3) is a synthetic octapeptide analogue of the N-terminal sequence of SNAP-25, a protein integral to the SNARE complex that mediates synaptic vesicle fusion at the neuromuscular junction. As an extended variant of the well-studied Snap-7 (Argireline) sequence, Snap-8 has been developed as a cosmetic research compound with enhanced affinity for the SNARE complex binding site. It is supplied here as a lyophilised research compound for in vitro investigation of neuromuscular signalling and cosmetic peptide biology.\u003c\/p\u003e\n\u003ch3\u003eMechanism of Action\u003c\/h3\u003e\n\u003cp\u003eSnap-8 competitively inhibits SNARE complex formation by mimicking the N-terminal domain of SNAP-25, thereby interfering with the docking and fusion of acetylcholine-containing synaptic vesicles at the neuromuscular junction. This reduces acetylcholine exocytosis and attenuates the downstream muscle contraction signal. Compared to shorter analogues, Snap-8’s extended octapeptide sequence is hypothesised to confer greater binding affinity and selectivity for the SNARE complex, making it a refined tool for studying neuromodulatory peptide mechanisms in vitro.\u003c\/p\u003e\n\u003ch3\u003eResearch Applications\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003eSNARE complex inhibition and neurotransmitter vesicle fusion studies\u003c\/li\u003e\n\u003cli\u003eComparative neuromodulatory peptide potency assays\u003c\/li\u003e\n\u003cli\u003eAcetylcholine release and neuromuscular junction signalling research\u003c\/li\u003e\n\u003cli\u003eCosmetic peptide efficacy and skin biology investigation\u003c\/li\u003e\n\u003cli\u003eIn vitro muscle contraction inhibition modelling\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3\u003eSpecifications\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eMolecular Formula:\u003c\/strong\u003e \u003cmeta charset=\"utf-8\"\u003eC₄₁H₇₀N₁₆O₁₆S\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eMolecular Weight:\u003c\/strong\u003e 1075.2 g\/mol\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eCAS Number:\u003c\/strong\u003e 868844-74-0\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003ePurity:\u003c\/strong\u003e ≥98%\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eForm:\u003c\/strong\u003e Lyophilised powder\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eStorage:\u003c\/strong\u003e -20°C\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eShelf Life:\u003c\/strong\u003e 24 months\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cem\u003eThis product is intended for legitimate laboratory and analytical research use only. Not for diagnostic, therapeutic, or consumer use.\u003c\/em\u003e\u003c\/p\u003e","brand":"Vanta Labs","offers":[{"title":"10mg","offer_id":58103431528712,"sku":"SNAP8-10MG","price":19.9,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1049\/8886\/8872\/files\/snap-8.png?v=1782894268","url":"https:\/\/vantalabsuk.com\/products\/snap-8","provider":"Vanta Labs","version":"1.0","type":"link"}