{"product_id":"selank","title":"Selank","description":"\u003ch2\u003eSelank\u003c\/h2\u003e\n\u003cp\u003eSelank is a synthetic heptapeptide (TKPRPGP) developed at the Institute of Molecular Genetics of the Russian Academy of Sciences. It is a structural analogue of the endogenous immunomodulatory tetrapeptide tuftsin (TKPR), extended with a proline-glycine-proline (PGP) C-terminal sequence to enhance metabolic stability and prolong biological activity. Selank has been extensively studied in preclinical and clinical research for its anxiolytic, nootropic, and immunomodulatory properties, and is one of the most thoroughly characterised peptide anxiolytics in the Russian scientific literature.\u003c\/p\u003e\n\u003ch3\u003eMechanism of Action\u003c\/h3\u003e\n\u003cp\u003eSelank exerts its anxiolytic effects primarily through modulation of GABAergic neurotransmission, increasing the affinity of GABA-A receptors for GABA without direct benzodiazepine-site binding — producing anxiolysis without sedation or dependence. It also inhibits the enzymatic degradation of endogenous enkephalins, prolonging their activity at opioid receptors and contributing to mood stabilisation. Additionally, Selank upregulates BDNF expression in the hippocampus, modulates IL-6 and other cytokine levels, and influences serotonergic and dopaminergic neurotransmission, supporting its investigation across anxiety, cognition, and neuroimmune research.\u003c\/p\u003e\n\u003ch3\u003eResearch Applications\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003eGABAergic modulation and anxiolytic mechanism studies\u003c\/li\u003e\n\u003cli\u003eEnkephalin degradation inhibition and opioid receptor signalling research\u003c\/li\u003e\n\u003cli\u003eBDNF expression and neuroplasticity investigation\u003c\/li\u003e\n\u003cli\u003eNeuroimmune modulation and cytokine regulation research\u003c\/li\u003e\n\u003cli\u003eAnxiety, stress resilience, and cognitive performance modelling\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3\u003eSpecifications\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eMolecular Formula:\u003c\/strong\u003e \u003cmeta charset=\"utf-8\"\u003eC₃₃H₅₇N₁₁O₉\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eMolecular Weight:\u003c\/strong\u003e 751.9 g\/mol\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eCAS Number:\u003c\/strong\u003e 129954-34-3\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003ePurity:\u003c\/strong\u003e ≥98%\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eForm:\u003c\/strong\u003e Lyophilised powder\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eStorage:\u003c\/strong\u003e -20°C\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eShelf Life:\u003c\/strong\u003e 24 months\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cem\u003eThis product is intended for legitimate laboratory and analytical research use only. Not for diagnostic, therapeutic, or consumer use.\u003c\/em\u003e\u003c\/p\u003e","brand":"Vanta Labs","offers":[{"title":"5mg","offer_id":58103430840584,"sku":"SELANK-5MG","price":14.5,"currency_code":"GBP","in_stock":true},{"title":"10mg","offer_id":58103430873352,"sku":"SELANK-10MG","price":24.99,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1049\/8886\/8872\/files\/selank.png?v=1782895443","url":"https:\/\/vantalabsuk.com\/products\/selank","provider":"Vanta Labs","version":"1.0","type":"link"}