{"product_id":"hexarelin","title":"Hexarelin Acetate","description":"\u003ch2\u003eHexarelin Acetate\u003c\/h2\u003e\n\u003cp\u003eHexarelin Acetate is a research-grade synthetic hexapeptide and potent ghrelin receptor (GHS-R1a) agonist, developed for preclinical investigation of growth hormone secretion, cardiac function, and neuroendocrine signalling. As one of the most potent GHRPs characterised to date, Hexarelin exhibits a high binding affinity for GHS-R1a and has been studied extensively in experimental models of GH axis regulation, cardioprotection, and hypothalamic-pituitary function.\u003c\/p\u003e\n\u003ch3\u003eMechanism of Action\u003c\/h3\u003e\n\u003cp\u003eHexarelin binds with high affinity to the ghrelin receptor (GHS-R1a) on pituitary somatotrophs and hypothalamic neurons, activating phospholipase C and protein kinase C signalling cascades to stimulate robust GH secretion. It also partially antagonises somatostatin tone, amplifying GH pulse amplitude. Notably, Hexarelin has been shown to bind to CD36 and the growth hormone secretagogue receptor type 1b (GHS-R1b), and preclinical studies have demonstrated direct cardioprotective effects independent of GH release, including attenuation of ischaemia-reperfusion injury and modulation of cardiac contractility via CD36-mediated signalling.\u003c\/p\u003e\n\u003ch3\u003eResearch Applications\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003eGH secretagogue pharmacology and pituitary function studies\u003c\/li\u003e\n\u003cli\u003eGhrelin receptor (GHS-R1a) signalling and binding affinity research\u003c\/li\u003e\n\u003cli\u003eCardioprotection and ischaemia-reperfusion injury modelling\u003c\/li\u003e\n\u003cli\u003eCD36 receptor signalling and cardiac function investigation\u003c\/li\u003e\n\u003cli\u003eGH\/IGF-1 axis and anabolic signalling studies\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3\u003eSpecifications\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eMolecular Formula:\u003c\/strong\u003e \u003cmeta charset=\"utf-8\"\u003eC₄₇H₅₈N₁₂O₆\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eCAS Number:\u003c\/strong\u003e 140703-51-1\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003ePurity:\u003c\/strong\u003e ≥98%\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eMolecular Weight:\u003c\/strong\u003e 887.0 g\/mol (acetate salt)\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eForm:\u003c\/strong\u003e Lyophilised powder\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eStorage:\u003c\/strong\u003e -20°C\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eShelf Life:\u003c\/strong\u003e 24 months\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cem\u003eThis product is intended for legitimate laboratory and analytical research use only. Not for diagnostic, therapeutic, or consumer use.\u003c\/em\u003e\u003c\/p\u003e","brand":"Vanta Labs","offers":[{"title":"2mg","offer_id":58103428055304,"sku":"HEXAR-2MG","price":12.0,"currency_code":"GBP","in_stock":true},{"title":"5mg","offer_id":58103428088072,"sku":"HEXAR-5MG","price":26.99,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1049\/8886\/8872\/files\/hexarelin-acetate.png?v=1782941304","url":"https:\/\/vantalabsuk.com\/products\/hexarelin","provider":"Vanta Labs","version":"1.0","type":"link"}