{"product_id":"hcg","title":"HCG","description":"\u003ch2\u003eHCG (Human Chorionic Gonadotropin)\u003c\/h2\u003e\n\u003cp\u003eHCG (Human Chorionic Gonadotropin) is a research-grade recombinant glycoprotein hormone structurally homologous to luteinising hormone (LH), developed for preclinical investigation of gonadal steroidogenesis, Leydig cell function, and reproductive endocrinology. Endogenously produced by the syncytiotrophoblast during early pregnancy, HCG acts as a potent LH receptor agonist and is widely used in experimental models of testosterone biosynthesis, spermatogenesis, and HPG axis regulation.\u003c\/p\u003e\n\u003ch3\u003eMechanism of Action\u003c\/h3\u003e\n\u003cp\u003eHCG binds to the LH\/hCG receptor (LHCGR) on Leydig cells in the testes and theca cells in the ovary, activating adenylyl cyclase via Gs protein coupling and increasing intracellular cAMP. This triggers the StAR protein-mediated transport of cholesterol into the mitochondria and the subsequent enzymatic cascade of steroidogenesis, culminating in testosterone (in males) or oestradiol and progesterone (in females) production. HCG also supports Sertoli cell function and spermatogenesis indirectly through testosterone-mediated signalling, and has been studied for its role in luteal phase support and corpus luteum maintenance.\u003c\/p\u003e\n\u003ch3\u003eResearch Applications\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003eLeydig cell steroidogenesis and testosterone biosynthesis studies\u003c\/li\u003e\n\u003cli\u003eLH\/hCG receptor (LHCGR) signalling research\u003c\/li\u003e\n\u003cli\u003eHPG axis regulation and gonadotropin biology investigation\u003c\/li\u003e\n\u003cli\u003eSpermatogenesis and male reproductive endocrinology modelling\u003c\/li\u003e\n\u003cli\u003eOvarian function, luteal phase, and corpus luteum research\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3\u003eSpecifications\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eMolecular Formula:\u003c\/strong\u003e \u003cmeta charset=\"utf-8\"\u003eC₁₁₀₅H₁₇₇₀N₃₁₈O₃₃₆S₂₆\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eCAS Number:\u003c\/strong\u003e \u003cmeta charset=\"utf-8\"\u003e9002-61-3\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003ePurity:\u003c\/strong\u003e ≥98%\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eMolecular Weight:\u003c\/strong\u003e ~36,700 Da (glycosylated)\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eForm:\u003c\/strong\u003e Lyophilised powder\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eStorage:\u003c\/strong\u003e -20°C\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eShelf Life:\u003c\/strong\u003e 24 months\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cem\u003eThis product is intended for legitimate laboratory and analytical research use only. Not for diagnostic, therapeutic, or consumer use.\u003c\/em\u003e\u003c\/p\u003e","brand":"Vanta Labs","offers":[{"title":"1000 IU","offer_id":58103427924232,"sku":"HCG-1000IU","price":39.99,"currency_code":"GBP","in_stock":true},{"title":"2000 IU","offer_id":58103427957000,"sku":"HCG-2000IU","price":59.99,"currency_code":"GBP","in_stock":true},{"title":"5000 IU","offer_id":58103427989768,"sku":"HCG-5000IU","price":89.99,"currency_code":"GBP","in_stock":true},{"title":"10000 IU","offer_id":58103428022536,"sku":"HCG-10000IU","price":130.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1049\/8886\/8872\/files\/hcg.png?v=1782941253","url":"https:\/\/vantalabsuk.com\/products\/hcg","provider":"Vanta Labs","version":"1.0","type":"link"}