{"product_id":"ghrp-6","title":"GHRP-6 Acetate","description":"\u003ch2\u003eGHRP-6 Acetate\u003c\/h2\u003e\n\u003cp\u003eGHRP-6 Acetate (Growth Hormone-Releasing Peptide-6) is a research-grade synthetic hexapeptide and first-generation ghrelin receptor (GHS-R1a) agonist, developed for preclinical investigation of growth hormone secretion, appetite regulation, and gastric motility. As the prototypical GHRP, GHRP-6 has been extensively characterised in experimental models and remains a key reference compound in GH secretagogue pharmacology, particularly for studies examining the orexigenic and GH-releasing properties of ghrelin receptor activation.\u003c\/p\u003e\n\u003ch3\u003eMechanism of Action\u003c\/h3\u003e\n\u003cp\u003eGHRP-6 binds to the ghrelin receptor (GHS-R1a) on pituitary somatotrophs and hypothalamic neurons, stimulating GH release through phospholipase C and protein kinase C signalling cascades. It also binds to the CD36 scavenger receptor, which mediates its pronounced appetite-stimulating (orexigenic) effect — a distinguishing feature compared to later-generation GHRPs. GHRP-6 partially antagonises somatostatin tone and acts synergistically with GHRH to amplify GH pulse amplitude, making it a useful tool for studying the interplay between these two regulatory axes.\u003c\/p\u003e\n\u003ch3\u003eResearch Applications\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003eGH secretagogue pharmacology and pituitary function studies\u003c\/li\u003e\n\u003cli\u003eGhrelin receptor (GHS-R1a) and CD36 receptor signalling research\u003c\/li\u003e\n\u003cli\u003eAppetite regulation and orexigenic pathway investigation\u003c\/li\u003e\n\u003cli\u003eGH\/IGF-1 axis and anabolic signalling modelling\u003c\/li\u003e\n\u003cli\u003eGastric motility and gastrointestinal function studies\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3\u003eSpecifications\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eMolecular Formula:\u003c\/strong\u003e C₄₆H₅₆N₁₀O₆ · C₂H₄O₂\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eCAS Number:\u003c\/strong\u003e \u003cmeta charset=\"utf-8\"\u003e145177-42-0\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003ePurity:\u003c\/strong\u003e ≥98%\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eMolecular Weight:\u003c\/strong\u003e \u003cmeta charset=\"utf-8\"\u003e1053.20 g\/mol\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eForm:\u003c\/strong\u003e Lyophilised powder\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eStorage:\u003c\/strong\u003e -20°C\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eShelf Life:\u003c\/strong\u003e 24 months\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cem\u003eThis product is intended for legitimate laboratory and analytical research use only. Not for diagnostic, therapeutic, or consumer use.\u003c\/em\u003e\u003c\/p\u003e","brand":"Vanta Labs","offers":[{"title":"5mg","offer_id":58103427596552,"sku":"GHRP6-5MG","price":14.5,"currency_code":"GBP","in_stock":true},{"title":"10mg","offer_id":58103427629320,"sku":"GHRP6-10MG","price":22.5,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1049\/8886\/8872\/files\/ghrp-6-acetate.png?v=1782940115","url":"https:\/\/vantalabsuk.com\/products\/ghrp-6","provider":"Vanta Labs","version":"1.0","type":"link"}