{"product_id":"ghrp-2","title":"GHRP-2 Acetate","description":"\u003ch2\u003eGHRP-2 Acetate\u003c\/h2\u003e\u003cp\u003eGHRP-2 Acetate (Growth Hormone-Releasing Peptide-2) is a research-grade synthetic hexapeptide and potent ghrelin receptor (GHS-R1a) agonist, developed for preclinical investigation of growth hormone secretion, appetite regulation, and metabolic signalling. As a second-generation GHRP, GHRP-2 exhibits greater GH-releasing potency than GHRP-6 with a comparatively reduced orexigenic effect, making it a widely used tool compound in GH axis research and neuroendocrine pharmacology.\u003c\/p\u003e\u003ch3\u003eMechanism of Action\u003c\/h3\u003e\u003cp\u003eGHRP-2 binds to and activates the ghrelin receptor (GHS-R1a) on pituitary somatotrophs and hypothalamic neurons, stimulating GH release through a mechanism distinct from and complementary to GHRH. It activates phospholipase C and protein kinase C signalling cascades, increasing intracellular calcium and triggering GH secretion. GHRP-2 also partially antagonises somatostatin tone, further amplifying GH pulse amplitude. Unlike GHRP-6, GHRP-2 has a lower affinity for the CD36 receptor, resulting in a reduced appetite-stimulating effect while maintaining robust GH secretagogue activity.\u003c\/p\u003e\u003ch3\u003eResearch Applications\u003c\/h3\u003e\u003cul\u003e\n\u003cli\u003eGH secretagogue pharmacology and pituitary function studies\u003c\/li\u003e\n\u003cli\u003eGhrelin receptor (GHS-R1a) signalling research\u003c\/li\u003e\n\u003cli\u003eGH\/IGF-1 axis and anabolic signalling investigation\u003c\/li\u003e\n\u003cli\u003eSomatostatin antagonism and GH pulse modulation\u003c\/li\u003e\n\u003cli\u003eAppetite regulation and metabolic signalling research\u003c\/li\u003e\n\u003c\/ul\u003e\u003ch3\u003eSpecifications\u003c\/h3\u003e\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eMolecular Formula:\u003c\/strong\u003e C₄₅H₅₅N₉O₆ · C₂H₄O₂\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eCAS Number:\u003c\/strong\u003e 158861-67-7\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003ePurity:\u003c\/strong\u003e ≥98%\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eMolecular Weight:\u003c\/strong\u003e 817.9 g\/mol (acetate salt)\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eForm:\u003c\/strong\u003e Lyophilised powder\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eStorage:\u003c\/strong\u003e -20°C\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eShelf Life:\u003c\/strong\u003e 24 months\u003c\/li\u003e\n\u003c\/ul\u003e\u003cp\u003e\u003cem\u003eThis product is intended for legitimate laboratory and analytical research use only. Not for diagnostic, therapeutic, or consumer use.\u003c\/em\u003e\u003c\/p\u003e","brand":"Vanta Labs","offers":[{"title":"5mg","offer_id":58103427498248,"sku":"GHRP2-5MG","price":9.5,"currency_code":"GBP","in_stock":true},{"title":"10mg","offer_id":58103427531016,"sku":"GHRP2-10MG","price":13.5,"currency_code":"GBP","in_stock":true},{"title":"15mg","offer_id":58103427563784,"sku":"GHRP2-15MG","price":17.99,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1049\/8886\/8872\/files\/ghrp-2-acetate.png?v=1782940028","url":"https:\/\/vantalabsuk.com\/products\/ghrp-2","provider":"Vanta Labs","version":"1.0","type":"link"}