{"product_id":"epo","title":"EPO","description":"\u003ch2\u003eEPO (Erythropoietin)\u003c\/h2\u003e\u003cp\u003eEPO (Erythropoietin) is a research-grade recombinant glycoprotein hormone developed for preclinical investigation of erythropoiesis, hypoxia signalling, and haematopoietic regulation. Endogenously produced primarily by the kidneys in response to hypoxia, erythropoietin is the principal regulator of red blood cell production, acting on erythroid progenitor cells in the bone marrow. Recombinant EPO is a well-characterised tool compound used extensively in haematology, nephrology, and oxygen transport research.\u003c\/p\u003e\u003ch3\u003eMechanism of Action\u003c\/h3\u003e\u003cp\u003eEPO binds to the erythropoietin receptor (EPOR) on erythroid progenitor cells in the bone marrow, activating the JAK2\/STAT5 signalling pathway. This promotes the proliferation, differentiation, and survival of erythroid progenitors, ultimately increasing circulating red blood cell mass and haemoglobin concentration. Beyond erythropoiesis, EPO receptors have been identified in neural, cardiac, and endothelial tissues, and preclinical research has explored its cytoprotective and anti-apoptotic roles in non-haematopoietic contexts including neuroprotection and cardiac ischaemia models.\u003c\/p\u003e\u003ch3\u003eResearch Applications\u003c\/h3\u003e\u003cul\u003e\n\u003cli\u003eErythropoiesis and red blood cell production studies\u003c\/li\u003e\n\u003cli\u003eJAK2\/STAT5 signalling pathway research\u003c\/li\u003e\n\u003cli\u003eHypoxia response and HIF pathway investigation\u003c\/li\u003e\n\u003cli\u003eNeuroprotection and cytoprotection modelling\u003c\/li\u003e\n\u003cli\u003eAnaemia and haematopoietic disorder research models\u003c\/li\u003e\n\u003c\/ul\u003e\u003ch3\u003eSpecifications\u003c\/h3\u003e\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eMolecular Formula:\u003c\/strong\u003e Recombinant glycoprotein\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eCAS Number:\u003c\/strong\u003e 113427-24-0\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003ePurity:\u003c\/strong\u003e ≥98%\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eMolecular Weight:\u003c\/strong\u003e ~30,400 Da (glycosylated)\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eForm:\u003c\/strong\u003e Lyophilised powder\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eStorage:\u003c\/strong\u003e -20°C\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eShelf Life:\u003c\/strong\u003e 24 months\u003c\/li\u003e\n\u003c\/ul\u003e\u003cp\u003e\u003cem\u003eThis product is intended for legitimate laboratory and analytical research use only. Not for diagnostic, therapeutic, or consumer use.\u003c\/em\u003e\u003c\/p\u003e","brand":"Vanta Labs","offers":[{"title":"3000 IU","offer_id":58103427367176,"sku":"EPO-3000IU","price":85.99,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1049\/8886\/8872\/files\/epo.png?v=1782938285","url":"https:\/\/vantalabsuk.com\/products\/epo","provider":"Vanta Labs","version":"1.0","type":"link"}