{"product_id":"cjc-1295-no-dac-ipamorelin","title":"CJC-1295 (No DAC) + Ipamorelin","description":"\u003ch2\u003eCJC-1295 (No DAC) + Ipamorelin\u003c\/h2\u003e\u003cp\u003eCJC-1295 (No DAC) + Ipamorelin is a research-grade peptide blend combining two complementary growth hormone secretagogues for preclinical investigation of the GH\/IGF-1 axis. CJC-1295 (No DAC) is a GHRH analogue that stimulates pituitary somatotrophs, while Ipamorelin is a selective ghrelin receptor (GHS-R1a) agonist that promotes GH release through a distinct, independent pathway. Together, they are studied for their synergistic effects on pulsatile GH secretion in experimental models.\u003c\/p\u003e\u003ch3\u003eMechanism of Action\u003c\/h3\u003e\u003cp\u003eCJC-1295 (No DAC) activates the GHRH receptor on pituitary somatotrophs, stimulating GH synthesis and release. Ipamorelin acts on the ghrelin receptor (GHS-R1a) to amplify GH secretion through a separate intracellular signalling cascade involving phospholipase C and protein kinase C. The combination produces additive or synergistic GH release by engaging both receptor pathways simultaneously, while Ipamorelin's high selectivity minimises off-target effects on cortisol and prolactin secretion observed with earlier GHRPs.\u003c\/p\u003e\u003ch3\u003eResearch Applications\u003c\/h3\u003e\u003cul\u003e\n\u003cli\u003eSynergistic GH secretagogue pharmacology studies\u003c\/li\u003e\n\u003cli\u003eGH\/IGF-1 axis and pituitary function investigation\u003c\/li\u003e\n\u003cli\u003eGhrelin receptor (GHS-R1a) signalling research\u003c\/li\u003e\n\u003cli\u003eAnabolic and metabolic regulation modelling\u003c\/li\u003e\n\u003cli\u003eCombination peptide therapy and receptor crosstalk studies\u003c\/li\u003e\n\u003c\/ul\u003e\u003ch3\u003eSpecifications\u003c\/h3\u003e\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eComposition:\u003c\/strong\u003e CJC-1295 (No DAC) + Ipamorelin peptide blend\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eMolecular Formula:\u003c\/strong\u003e Peptide blend\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eCAS Number:\u003c\/strong\u003e N\/A (blend)\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003ePurity:\u003c\/strong\u003e ≥98%\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eForm:\u003c\/strong\u003e Lyophilised powder\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eStorage:\u003c\/strong\u003e -20°C\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eShelf Life:\u003c\/strong\u003e 24 months\u003c\/li\u003e\n\u003c\/ul\u003e\u003cp\u003e\u003cem\u003eThis product is intended for legitimate laboratory and analytical research use only. Not for diagnostic, therapeutic, or consumer use.\u003c\/em\u003e\u003c\/p\u003e","brand":"Vanta Labs","offers":[{"title":"10mg","offer_id":58103427006728,"sku":"CJCIPA-10MG","price":34.95,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1049\/8886\/8872\/files\/CJC-1295_Plus_IPAMORELIN.png?v=1783026439","url":"https:\/\/vantalabsuk.com\/products\/cjc-1295-no-dac-ipamorelin","provider":"Vanta Labs","version":"1.0","type":"link"}