{"product_id":"cagrilintide","title":"Cagrilintide","description":"\u003ch2\u003eCagrilintide\u003c\/h2\u003e\n\u003cp\u003eCagrilintide is a long-acting amylin analogue developed for preclinical investigation of metabolic regulation, appetite control, and body weight modulation. As a synthetic analogue of human amylin, it is designed to resist enzymatic degradation and provide sustained receptor engagement, making it a valuable tool compound for studying amylin receptor biology and its role in energy homeostasis. Cagrilintide has been investigated in combination with GLP-1 receptor agonists for its additive effects on satiety and metabolic parameters.\u003c\/p\u003e\n\u003ch3\u003eMechanism of Action\u003c\/h3\u003e\n\u003cp\u003eCagrilintide acts as an agonist at amylin receptors (AMY1, AMY2, AMY3), which are heterodimeric complexes of the calcitonin receptor and receptor activity-modifying proteins (RAMPs). Activation of these receptors in the hypothalamus and brainstem suppresses appetite, slows gastric emptying, and reduces postprandial glucagon secretion. Its extended half-life relative to native amylin is achieved through fatty acid conjugation, enabling once-weekly dosing paradigms in research models.\u003c\/p\u003e\n\u003ch3\u003eResearch Applications\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003eAmylin receptor pharmacology and signalling studies\u003c\/li\u003e\n\u003cli\u003eAppetite regulation and satiety pathway investigation\u003c\/li\u003e\n\u003cli\u003eMetabolic syndrome and obesity modelling\u003c\/li\u003e\n\u003cli\u003eCombination peptide therapy research (e.g. with GLP-1 analogues)\u003c\/li\u003e\n\u003cli\u003eGastric motility and postprandial glucagon studies\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3\u003eSpecifications\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eMolecular Formula:\u003c\/strong\u003e \u003cmeta charset=\"utf-8\"\u003eC₁₉₄H₃₁₂N₅₄O₅₉S₂\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eCAS Number:\u003c\/strong\u003e 2173044-15-8\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003ePurity:\u003c\/strong\u003e ≥98%\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eMolecular Weight:\u003c\/strong\u003e 4421.1 g\/mol\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eForm:\u003c\/strong\u003e Lyophilised powder\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eStorage:\u003c\/strong\u003e -20°C\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eShelf Life:\u003c\/strong\u003e 24 months\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cem\u003eThis product is intended for legitimate laboratory and analytical research use only. Not for diagnostic, therapeutic, or consumer use.\u003c\/em\u003e\u003c\/p\u003e","brand":"Vanta Labs","offers":[{"title":"5mg","offer_id":58103426679048,"sku":"CAGRI-5MG","price":20.99,"currency_code":"GBP","in_stock":true},{"title":"10mg","offer_id":58103426711816,"sku":"CAGRI-10MG","price":39.99,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1049\/8886\/8872\/files\/cagrilintide.png?v=1782935141","url":"https:\/\/vantalabsuk.com\/products\/cagrilintide","provider":"Vanta Labs","version":"1.0","type":"link"}