{"title":"Longevity \u0026 Anti-Ageing","description":"\u003cp\u003ePeptides studied for cellular senescence, mitochondrial function, and longevity pathways. Includes bioregulator peptides and compounds researched for healthy ageing and lifespan extension.\u003c\/p\u003e","products":[{"product_id":"cardiogen","title":"Cardiogen","description":"\u003ch2\u003eCardiogen\u003c\/h2\u003e\n\u003cp\u003eCardiogen is a research-grade tetrapeptide of Russian bioregulator origin, developed for preclinical investigation of cardiac tissue function and myocardial biology. As part of the Khavinson peptide bioregulator series, Cardiogen is a short-chain peptide designed to interact with cardiac cell DNA and modulate gene expression associated with cardiomyocyte function and tissue homeostasis. It is supplied as a lyophilised extract for use in in vitro and in vivo research models.\u003c\/p\u003e\n\u003ch3\u003eMechanism of Action\u003c\/h3\u003e\n\u003cp\u003eCardiogen is hypothesised to act as a gene expression modulator, interacting with chromatin and influencing the transcription of genes involved in cardiac cell differentiation, protein synthesis, and tissue repair. Peptide bioregulators of this class are thought to exhibit tissue-specific activity by binding to complementary DNA sequences in target cells, thereby restoring or maintaining normal cellular function in aged or damaged tissue. Research has focused on its potential role in cardiomyocyte viability and functional recovery in experimental models.\u003c\/p\u003e\n\u003ch3\u003eResearch Applications\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003eCardiomyocyte biology and cardiac tissue homeostasis studies\u003c\/li\u003e\n\u003cli\u003ePeptide bioregulator gene expression modulation research\u003c\/li\u003e\n\u003cli\u003eMyocardial function and recovery modelling\u003c\/li\u003e\n\u003cli\u003eAgeing and cellular senescence investigation in cardiac tissue\u003c\/li\u003e\n\u003cli\u003eCytoprotection and tissue-specific peptide activity studies\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3\u003eSpecifications\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eMolecular Formula:\u003c\/strong\u003e \u003cmeta charset=\"utf-8\"\u003eC₁₈H₃₁N₇O₉\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eCAS Number:\u003c\/strong\u003e N\/A\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003ePurity:\u003c\/strong\u003e ≥98%\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eMolecular Weight:\u003c\/strong\u003e \u003cmeta charset=\"utf-8\"\u003e489.48 g\/mol\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eForm:\u003c\/strong\u003e Lyophilised extract\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eStorage:\u003c\/strong\u003e -20°C\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eShelf Life:\u003c\/strong\u003e 24 months\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cem\u003eThis product is intended for legitimate laboratory and analytical research use only. Not for diagnostic, therapeutic, or consumer use.\u003c\/em\u003e\u003c\/p\u003e","brand":"Vanta Labs","offers":[{"title":"5mg","offer_id":58103426744584,"sku":"CARDIO-5MG","price":36.99,"currency_code":"GBP","in_stock":true},{"title":"10mg","offer_id":58103426777352,"sku":"CARDIO-10MG","price":41.9,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1049\/8886\/8872\/files\/cardiogen.png?v=1782935256"},{"product_id":"epithalon","title":"Epithalon","description":"\u003ch2\u003eEpithalon\u003c\/h2\u003e\u003cp\u003eEpithalon (Epitalon) is a research-grade synthetic tetrapeptide analogue of Epithalamin, a natural polypeptide extract of the pineal gland, developed for preclinical investigation of telomere biology, ageing, and neuroendocrine regulation. Originally developed by Professor Vladimir Khavinson at the St. Petersburg Institute of Bioregulation and Gerontology, Epithalon has been studied extensively in experimental models for its ability to activate telomerase, elongate telomeres, and modulate pineal gland function. It is supplied as a lyophilised powder for use in in vitro and in vivo research.\u003c\/p\u003e\u003ch3\u003eMechanism of Action\u003c\/h3\u003e\u003cp\u003eEpithalon is hypothesised to stimulate the expression of telomerase (hTERT), the enzyme responsible for maintaining telomere length in dividing cells, thereby counteracting replicative senescence. It also modulates the secretion of melatonin and other pineal hormones, influencing circadian rhythm regulation and antioxidant defence. Preclinical studies have demonstrated effects on cell cycle regulation, DNA repair, and the expression of genes associated with longevity and stress resistance, making it a key tool compound in experimental gerontology research.\u003c\/p\u003e\u003ch3\u003eResearch Applications\u003c\/h3\u003e\u003cul\u003e\n\u003cli\u003eTelomerase activation and telomere elongation studies\u003c\/li\u003e\n\u003cli\u003eCellular senescence and replicative ageing research\u003c\/li\u003e\n\u003cli\u003ePineal gland function and melatonin regulation investigation\u003c\/li\u003e\n\u003cli\u003eCircadian rhythm and neuroendocrine modulation modelling\u003c\/li\u003e\n\u003cli\u003eDNA repair and longevity gene expression studies\u003c\/li\u003e\n\u003c\/ul\u003e\u003ch3\u003eSpecifications\u003c\/h3\u003e\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eMolecular Formula:\u003c\/strong\u003e C₁₄H₂₂N₄O₉\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eCAS Number:\u003c\/strong\u003e 307297-39-8\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003ePurity:\u003c\/strong\u003e ≥98%\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eMolecular Weight:\u003c\/strong\u003e 390.3 g\/mol\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eForm:\u003c\/strong\u003e Lyophilised powder\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eStorage:\u003c\/strong\u003e -20°C\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eShelf Life:\u003c\/strong\u003e 24 months\u003c\/li\u003e\n\u003c\/ul\u003e\u003cp\u003e\u003cem\u003eThis product is intended for legitimate laboratory and analytical research use only. Not for diagnostic, therapeutic, or consumer use.\u003c\/em\u003e\u003c\/p\u003e","brand":"Vanta Labs","offers":[{"title":"10mg","offer_id":58103427301640,"sku":"EPITH-10MG","price":14.99,"currency_code":"GBP","in_stock":true},{"title":"50mg","offer_id":58103427334408,"sku":"EPITH-50MG","price":60.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1049\/8886\/8872\/files\/epithalon.png?v=1782938070"},{"product_id":"foxo4-dri","title":"FOXO4-DRI","description":"\u003ch2\u003eFOXO4-DRI\u003c\/h2\u003e\n\u003cp\u003eFOXO4-DRI is a research-grade D-amino acid retro-inverso peptide designed for preclinical investigation of cellular senescence, apoptosis, and tissue rejuvenation. Developed by Peter de Keizer and colleagues, FOXO4-DRI is a modified peptide that disrupts the interaction between the FOXO4 transcription factor and p53 in senescent cells, selectively triggering apoptosis in cells that have entered a state of permanent cell cycle arrest. It represents a significant tool compound in the emerging field of senolytic research.\u003c\/p\u003e\n\u003ch3\u003eMechanism of Action\u003c\/h3\u003e\n\u003cp\u003eIn senescent cells, FOXO4 forms a complex with p53 that sequesters p53 in the nucleus and prevents apoptosis, allowing senescent cells to persist and secrete pro-inflammatory factors (the senescence-associated secretory phenotype, SASP). FOXO4-DRI competitively disrupts this FOXO4–p53 interaction, freeing p53 to translocate to the mitochondria and initiate the intrinsic apoptotic cascade selectively in senescent cells. Non-senescent cells, which do not rely on this FOXO4–p53 interaction for survival, are largely unaffected, conferring a degree of selectivity that makes FOXO4-DRI a valuable senolytic research tool.\u003c\/p\u003e\n\u003ch3\u003eResearch Applications\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003eCellular senescence and senolytic activity studies\u003c\/li\u003e\n\u003cli\u003eFOXO4–p53 protein–protein interaction research\u003c\/li\u003e\n\u003cli\u003eSASP modulation and tissue inflammation investigation\u003c\/li\u003e\n\u003cli\u003eAge-related tissue dysfunction and rejuvenation modelling\u003c\/li\u003e\n\u003cli\u003eApoptosis pathway selectivity in senescent vs. healthy cells\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3\u003eSpecifications\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eMolecular Formula:\u003c\/strong\u003e \u003cmeta charset=\"utf-8\"\u003eC₂₂₈H₃₈₈N₈₆O₆₄\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eCAS Number:\u003c\/strong\u003e \u003cmeta charset=\"utf-8\"\u003e2460055-10-9\u003c\/li\u003e\n\u003cli\u003e\n\u003cmeta charset=\"utf-8\"\u003e\n\u003cspan class=\"T286Pc\" data-sfc-cp=\"\" data-sfc-root=\"ep\" data-sfc-cb=\"\" data-complete=\"true\" data-copy-service-computed-style='font-family: \"Google Sans\", Arial, sans-serif; font-size: 16px; font-weight: 400; margin: 0px; text-decoration: none; border-bottom: 0px rgb(230, 232, 240);'\u003e\u003cstrong class=\"Yjhzub\" data-sfc-root=\"ep\" data-sfc-cb=\"\" data-complete=\"true\" data-copy-service-computed-style='font-family: \"Google Sans\", Arial, sans-serif; font-size: 16px; font-weight: 700; margin: 0px; text-decoration: none; border-bottom: 0px rgb(230, 232, 240);'\u003eMolecular Weight:\u003c!--TgQPHd||[]--\u003e\u003c\/strong\u003e 5358.15 g\/mol\u003c!--TgQPHd||[]--\u003e\u003c\/span\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003ePurity:\u003c\/strong\u003e ≥98%\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eForm:\u003c\/strong\u003e Lyophilised powder\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eStorage:\u003c\/strong\u003e -20°C\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eShelf Life:\u003c\/strong\u003e 24 months\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cem\u003eThis product is intended for legitimate laboratory and analytical research use only. Not for diagnostic, therapeutic, or consumer use.\u003c\/em\u003e\u003c\/p\u003e","brand":"Vanta Labs","offers":[{"title":"10mg","offer_id":58103427399944,"sku":"FOXO4-10MG","price":69.99,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1049\/8886\/8872\/files\/foxo4-dri.png?v=1782938602"},{"product_id":"humanin","title":"Humanin","description":"\u003ch2\u003eHumanin\u003c\/h2\u003e\n\u003cp\u003eHumanin is a 21-amino acid mitochondria-derived peptide (MDP) encoded within the 16S ribosomal RNA gene of the mitochondrial genome — making it one of the first identified members of the mitochondrial-derived peptide family, alongside MOTS-c and SHLPs. It was originally discovered in 2001 by Nishimoto et al. during a screen for factors that protect neurons from Alzheimer’s disease-associated cell death, and has since been characterised as a pleiotropic cytoprotective peptide with roles in neuroprotection, metabolic regulation, cardiovascular protection, and longevity biology. Humanin circulates in human plasma and declines with age, positioning it as a research target in the biology of ageing and age-related disease.\u003c\/p\u003e\n\u003ch3\u003eMechanism of Action\u003c\/h3\u003e\n\u003cp\u003eHumanin exerts its cytoprotective effects through multiple receptor-dependent and receptor-independent mechanisms. It binds to a tripartite receptor complex comprising gp130, CNTFRα, and WSX-1 on the cell surface, activating JAK2\/STAT3 and PI3K\/Akt signalling pathways that promote cell survival and suppress apoptosis. Humanin also directly interacts with the pro-apoptotic protein BAX, preventing its mitochondrial translocation and cytochrome c release, thereby inhibiting the intrinsic apoptotic pathway. Additionally, Humanin activates AMPK and modulates insulin signalling via the IGF-1 receptor, contributing to its metabolic effects including improved insulin sensitivity and reduced hepatic lipid accumulation. In the CNS, Humanin protects neurons from amyloid-β toxicity, oxidative stress, and ER stress-induced apoptosis, making it a key research tool in neurodegeneration biology.\u003c\/p\u003e\n\u003ch3\u003eResearch Applications\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003eMitochondria-derived peptide (MDP) biology and mitochondrial-nuclear communication research\u003c\/li\u003e\n\u003cli\u003eNeuroprotection, amyloid-β toxicity, and Alzheimer’s disease preclinical models\u003c\/li\u003e\n\u003cli\u003eJAK2\/STAT3 and PI3K\/Akt cytoprotective signalling studies\u003c\/li\u003e\n\u003cli\u003eBAX-mediated apoptosis inhibition and mitochondrial integrity research\u003c\/li\u003e\n\u003cli\u003eAgeing biology, longevity, and age-related metabolic disease investigation\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3\u003eSpecifications\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eMolecular Formula:\u003c\/strong\u003e \u003cmeta charset=\"utf-8\"\u003e\n\u003cspan class=\"T286Pc\" data-sfc-cp=\"\" data-sfc-root=\"ep\" data-sfc-cb=\"\" data-complete=\"true\" data-copy-service-computed-style='font-family: \"Google Sans\", Arial, sans-serif; font-size: 16px; font-weight: 400; margin: 0px; text-decoration: none; border-bottom: 0px rgb(230, 232, 240);'\u003eC₁₁₉H₂₀₄N₃₄O₃₂S₂\u003c!--TgQPHd||[]--\u003e\u003c\/span\u003e\u003cspan data-copy-service-computed-style='font-family: \"Google Sans\", Arial, sans-serif; font-size: 16px; font-weight: 400; margin: 0px; text-decoration: none; border-bottom: 0px rgb(230, 232, 240);'\u003e\u003c!--TgQPHd||[]--\u003e\u003c\/span\u003e\u003c!--TgQPHd||[]--\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eMolecular Weight:\u003c\/strong\u003e \u003cmeta charset=\"utf-8\"\u003e2687.27 g\/mol\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eCAS Number:\u003c\/strong\u003e 330936-69-1\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003ePurity:\u003c\/strong\u003e ≥98%\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eForm:\u003c\/strong\u003e Lyophilised powder\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eStorage:\u003c\/strong\u003e -20°C\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eShelf Life:\u003c\/strong\u003e 24 months\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cem\u003eThis product is intended for legitimate laboratory and analytical research use only. Not for diagnostic, therapeutic, or consumer use.\u003c\/em\u003e\u003c\/p\u003e","brand":"Vanta Labs","offers":[{"title":"5mg","offer_id":58103428481288,"sku":"HUMAN-5MG","price":130.99,"currency_code":"GBP","in_stock":true},{"title":"10mg","offer_id":58103428514056,"sku":"HUMAN-10MG","price":210.99,"currency_code":"GBP","in_stock":true},{"title":"20mg","offer_id":58103428546824,"sku":"HUMAN-20MG","price":310.99,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1049\/8886\/8872\/files\/humanin.png?v=1782922952"},{"product_id":"mots-c","title":"MOTS-c","description":"\u003ch2\u003eMOTS-c\u003c\/h2\u003e\n\u003cp\u003eMOTS-c (Mitochondrial Open Reading Frame of the 12S rRNA-c) is a 16-amino acid mitochondria-derived peptide (MDP) encoded within the 12S ribosomal RNA gene of the mitochondrial genome. It was identified in 2015 by researchers at the University of Southern California as a novel mitochondrial signalling peptide with systemic metabolic regulatory functions. MOTS-c is one of a growing class of mitochondria-derived peptides that act as retrograde signals from the mitochondria to the nucleus and peripheral tissues, and has attracted significant research interest for its roles in metabolic regulation, insulin sensitivity, exercise adaptation, and longevity.\u003c\/p\u003e\n\u003ch3\u003eMechanism of Action\u003c\/h3\u003e\n\u003cp\u003eMOTS-c translocates from the mitochondria to the nucleus in response to metabolic stress, where it regulates nuclear gene expression by interacting with the antioxidant response element (ARE) pathway and activating AMPK signalling. In skeletal muscle, MOTS-c enhances glucose uptake and fatty acid oxidation by promoting GLUT4 translocation and inhibiting the folate cycle — a mechanism that reduces de novo purine synthesis and activates AMPK via AICAR accumulation. MOTS-c also modulates the FOXO1 and NRF2 transcription factors, supporting antioxidant defence and mitochondrial biogenesis, and has demonstrated exercise-mimetic effects in preclinical models.\u003c\/p\u003e\n\u003ch3\u003eResearch Applications\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003eMitochondria-derived peptide (MDP) signalling and retrograde communication studies\u003c\/li\u003e\n\u003cli\u003eAMPK activation, glucose metabolism, and insulin sensitivity research\u003c\/li\u003e\n\u003cli\u003eSkeletal muscle metabolic adaptation and exercise mimicry investigation\u003c\/li\u003e\n\u003cli\u003eFolate cycle inhibition and purine biosynthesis regulation research\u003c\/li\u003e\n\u003cli\u003eLongevity, ageing, and mitochondrial function preclinical models\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3\u003eSpecifications\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eMolecular Formula:\u003c\/strong\u003e \u003cmeta charset=\"utf-8\"\u003e\n\u003cspan class=\"T286Pc\" data-sfc-cp=\"\" data-sfc-root=\"ep\" data-sfc-cb=\"\" data-complete=\"true\" data-copy-service-computed-style='font-family: \"Google Sans\", Arial, sans-serif; font-size: 16px; font-weight: 400; margin: 0px; text-decoration: none; border-bottom: 0px rgb(230, 232, 240);'\u003eC₁₀₁H₁₅₂N₂₈O₂₂S₂\u003c!--TgQPHd||[]--\u003e\u003c\/span\u003e\u003cspan data-copy-service-computed-style='font-family: \"Google Sans\", Arial, sans-serif; font-size: 16px; font-weight: 400; margin: 0px; text-decoration: none; border-bottom: 0px rgb(230, 232, 240);'\u003e\u003c!--TgQPHd||[]--\u003e\u003c\/span\u003e\u003c!--TgQPHd||[]--\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eMolecular Weight:\u003c\/strong\u003e 2174.5 g\/mol\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eCAS Number:\u003c\/strong\u003e 1627580-64-6\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003ePurity:\u003c\/strong\u003e ≥98%\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eForm:\u003c\/strong\u003e Lyophilised powder\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eStorage:\u003c\/strong\u003e -20°C\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eShelf Life:\u003c\/strong\u003e 24 months\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cem\u003eThis product is intended for legitimate laboratory and analytical research use only. Not for diagnostic, therapeutic, or consumer use.\u003c\/em\u003e\u003c\/p\u003e","brand":"Vanta Labs","offers":[{"title":"5mg","offer_id":58103429792008,"sku":"MOTSC-5MG","price":18.0,"currency_code":"GBP","in_stock":true},{"title":"10mg","offer_id":58103429824776,"sku":"MOTSC-10MG","price":25.0,"currency_code":"GBP","in_stock":true},{"title":"40mg","offer_id":58103429857544,"sku":"MOTSC-40MG","price":59.99,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1049\/8886\/8872\/files\/mots-c.png?v=1782914605"},{"product_id":"ss-31","title":"SS-31 (Elamipretide)","description":"\u003ch2\u003eSS-31 (Elamipretide)\u003c\/h2\u003e\n\u003cp\u003eSS-31, also known as Elamipretide or MTP-131, is a synthetic tetrapeptide (D-Arg-2’,6’-Dmt-Lys-Phe-NH2) belonging to the Szeto-Schiller (SS) peptide family. It is specifically designed to target and concentrate within the inner mitochondrial membrane, where it interacts with cardiolipin — a phospholipid critical for mitochondrial cristae architecture and electron transport chain function. SS-31 has emerged as a leading research tool in mitochondrial biology, with a substantial body of preclinical literature supporting its investigation across ageing, ischaemia-reperfusion injury, and metabolic disease models.\u003c\/p\u003e\n\u003ch3\u003eMechanism of Action\u003c\/h3\u003e\n\u003cp\u003eSS-31 selectively partitions into the inner mitochondrial membrane due to its alternating aromatic and cationic residues, achieving mitochondrial concentrations several hundred-fold above cytoplasmic levels. It binds directly to cardiolipin, stabilising cristae morphology and preserving the structural integrity of electron transport chain supercomplexes (respirasomes). This interaction reduces mitochondrial reactive oxygen species (ROS) production, restores ATP synthesis efficiency, and inhibits cytochrome c peroxidase activity — collectively attenuating mitochondrial dysfunction and apoptotic signalling.\u003c\/p\u003e\n\u003ch3\u003eResearch Applications\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003eMitochondrial membrane dynamics and cardiolipin interaction studies\u003c\/li\u003e\n\u003cli\u003eElectron transport chain supercomplex stability and bioenergetics research\u003c\/li\u003e\n\u003cli\u003eIschaemia-reperfusion injury and cardiac protection models\u003c\/li\u003e\n\u003cli\u003eMitochondrial ROS production and oxidative stress investigation\u003c\/li\u003e\n\u003cli\u003eAgeing, sarcopenia, and metabolic disease preclinical models\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3\u003eSpecifications\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eMolecular Formula:\u003c\/strong\u003e \u003cmeta charset=\"utf-8\"\u003eC₃₂H₄₉N₉O₅\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eMolecular Weight:\u003c\/strong\u003e 639.8 g\/mol\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eCAS Number:\u003c\/strong\u003e 736992-21-5\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003ePurity:\u003c\/strong\u003e ≥98%\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eForm:\u003c\/strong\u003e Lyophilised powder\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eStorage:\u003c\/strong\u003e -20°C\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eShelf Life:\u003c\/strong\u003e 24 months\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cem\u003eThis product is intended for legitimate laboratory and analytical research use only. Not for diagnostic, therapeutic, or consumer use.\u003c\/em\u003e\u003c\/p\u003e","brand":"Vanta Labs","offers":[{"title":"10mg","offer_id":58103431594248,"sku":"SS31-10MG","price":28.99,"currency_code":"GBP","in_stock":true},{"title":"50mg","offer_id":58103431627016,"sku":"SS31-50MG","price":110.99,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1049\/8886\/8872\/files\/ss-31-elamipretide.png?v=1782893972"},{"product_id":"thymalin","title":"Thymalin","description":"\u003ch2\u003eThymalin\u003c\/h2\u003e\n\u003cp\u003eThymalin is a polypeptide thymic bioregulator isolated from the thymus glands of cattle, developed as part of the pioneering peptide bioregulator research programme led by Professor Vladimir Khavinson at the St. Petersburg Institute of Bioregulation and Gerontology. As a natural thymic extract, Thymalin contains a complex of low-molecular-weight peptides that have been investigated for their capacity to restore and modulate immune function, particularly in the context of age-related immunosenescence. It represents one of the earliest and most studied peptide bioregulators in the Russian gerontological research tradition.\u003c\/p\u003e\n\u003ch3\u003eMechanism of Action\u003c\/h3\u003e\n\u003cp\u003eThymalin is hypothesised to act by restoring the functional activity of T-lymphocytes and normalising the ratio of T-helper to T-suppressor cells. Its constituent peptides are thought to interact with nuclear chromatin in thymus-dependent immune cells, modulating gene expression associated with lymphocyte differentiation and proliferation. Preclinical studies have demonstrated effects on IL-2 production, NK cell activity, and the restoration of thymic hormone levels in aged subjects, consistent with a broad immunorestoration mechanism.\u003c\/p\u003e\n\u003ch3\u003eResearch Applications\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003eAge-related immunosenescence and thymic involution research\u003c\/li\u003e\n\u003cli\u003eT-lymphocyte differentiation and functional restoration studies\u003c\/li\u003e\n\u003cli\u003eNK cell activity and innate immune modulation investigation\u003c\/li\u003e\n\u003cli\u003ePeptide bioregulator mechanism and epigenetic research\u003c\/li\u003e\n\u003cli\u003eLongevity and healthy ageing preclinical models\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3\u003eSpecifications\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eMolecular Formula:\u003c\/strong\u003e \u003cmeta charset=\"utf-8\"\u003eC₃₃H₅₄N₁₂O₁₅\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eMolecular Weight:\u003c\/strong\u003e \u003cmeta charset=\"utf-8\"\u003e858.86 g\/mol\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eCAS Number:\u003c\/strong\u003e \u003cmeta charset=\"utf-8\"\u003e63958-90-7\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003ePurity:\u003c\/strong\u003e ≥98%\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eForm:\u003c\/strong\u003e Lyophilised powder\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eStorage:\u003c\/strong\u003e -20°C\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eShelf Life:\u003c\/strong\u003e 24 months\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cem\u003eThis product is intended for legitimate laboratory and analytical research use only. Not for diagnostic, therapeutic, or consumer use.\u003c\/em\u003e\u003c\/p\u003e","brand":"Vanta Labs","offers":[{"title":"10mg","offer_id":58103431987464,"sku":"THYMAL-10MG","price":24.9,"currency_code":"GBP","in_stock":true},{"title":"20mg","offer_id":58103432020232,"sku":"THYMAL-20MG","price":41.99,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1049\/8886\/8872\/files\/thymalin_1b6e1325-548a-4b7d-a7c1-96f9025bf57a.png?v=1782893294"},{"product_id":"vesugen","title":"Vesugen","description":"\u003ch2\u003eVesugen\u003c\/h2\u003e\n\u003cp\u003eVesugen is a short-chain tripeptide of Russian bioregulator origin, developed as part of the Khavinson peptide series. It is classified as a vascular bioregulator, with preclinical research suggesting a role in supporting endothelial function and vascular tissue homeostasis. Vesugen has been investigated for its potential to modulate gene expression in vascular smooth muscle and endothelial cells, making it a subject of interest in cardiovascular and ageing research.\u003c\/p\u003e\n\u003ch3\u003eMechanism of Action\u003c\/h3\u003e\n\u003cp\u003eVesugen is hypothesised to act as a peptide bioregulator by interacting with specific DNA promoter regions in vascular tissue, thereby influencing the transcription of genes associated with endothelial integrity and smooth muscle function. This epigenetic-like mechanism is consistent with the broader Khavinson bioregulator model, in which short peptides restore age-related decline in tissue-specific gene expression.\u003c\/p\u003e\n\u003ch3\u003eResearch Applications\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003eVascular endothelial function and integrity studies\u003c\/li\u003e\n\u003cli\u003eCardiovascular ageing and longevity research\u003c\/li\u003e\n\u003cli\u003eSmooth muscle cell gene expression modelling\u003c\/li\u003e\n\u003cli\u003ePeptide bioregulator mechanism investigation\u003c\/li\u003e\n\u003cli\u003eAngiogenesis and microcirculation research\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3\u003eSpecifications\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eMolecular Formula:\u003c\/strong\u003e \u003cmeta charset=\"utf-8\"\u003eC₁₅H₂₆N₄O₈\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eMolecular Weight:\u003c\/strong\u003e \u003cmeta charset=\"utf-8\"\u003e390.39 g\/mol\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eCAS Number:\u003c\/strong\u003e \u003cmeta charset=\"utf-8\"\u003e204271-66-9\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003ePurity:\u003c\/strong\u003e ≥98%\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eForm:\u003c\/strong\u003e Lyophilised powder\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eStorage:\u003c\/strong\u003e -20°C\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eShelf Life:\u003c\/strong\u003e 24 months\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cem\u003eThis product is intended for legitimate laboratory and analytical research use only. Not for diagnostic, therapeutic, or consumer use.\u003c\/em\u003e\u003c\/p\u003e","brand":"Vanta Labs","offers":[{"title":"5mg","offer_id":58103432708360,"sku":"VESUG-5MG","price":32.99,"currency_code":"GBP","in_stock":true},{"title":"10mg","offer_id":58103432741128,"sku":"VESUG-10MG","price":44.99,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1049\/8886\/8872\/files\/vesugen.png?v=1782892406"}],"url":"https:\/\/vantalabsuk.com\/collections\/longevity-anti-ageing.oembed","provider":"Vanta Labs","version":"1.0","type":"link"}