{"title":"Hormones \u0026 Fertility Peptides","description":"\u003cp\u003eResearch-grade hormones and fertility-related peptides for laboratory use. Includes gonadotropins, reproductive hormones, and related compounds studied in endocrinology and reproductive biology research.\u003c\/p\u003e\u003cp\u003e\u003cem\u003eFor research and laboratory use only. Not intended for human or veterinary use.\u003c\/em\u003e\u003c\/p\u003e","products":[{"product_id":"gonadorelin","title":"Gonadorelin","description":"\u003ch2\u003eGonadorelin\u003c\/h2\u003e\u003cp\u003eGonadorelin is a research-grade synthetic decapeptide identical in structure to endogenous gonadotropin-releasing hormone (GnRH), developed for preclinical investigation of the hypothalamic-pituitary-gonadal (HPG) axis, reproductive endocrinology, and pituitary gonadotroph function. As the native GnRH sequence, Gonadorelin stimulates the pulsatile release of luteinising hormone (LH) and follicle-stimulating hormone (FSH) from the anterior pituitary, making it a key tool compound for studying gonadotropin regulation, fertility biology, and sex steroid feedback mechanisms.\u003c\/p\u003e\u003ch3\u003eMechanism of Action\u003c\/h3\u003e\u003cp\u003eGonadorelin binds to GnRH receptors (GnRHR) on pituitary gonadotroph cells, activating Gq\/11-coupled phospholipase C signalling and triggering intracellular calcium release and protein kinase C activation. This leads to the synthesis and pulsatile secretion of LH and FSH, which in turn stimulate gonadal steroidogenesis and gametogenesis. The pulsatile nature of GnRH signalling is critical: continuous exposure leads to receptor downregulation and gonadotropin suppression, while pulsatile administration maintains or stimulates the HPG axis — a distinction of significant research relevance.\u003c\/p\u003e\u003ch3\u003eResearch Applications\u003c\/h3\u003e\u003cul\u003e\n\u003cli\u003eHPG axis regulation and gonadotropin secretion studies\u003c\/li\u003e\n\u003cli\u003eGnRH receptor signalling and pituitary gonadotroph biology\u003c\/li\u003e\n\u003cli\u003eLH and FSH pulsatility and reproductive endocrinology research\u003c\/li\u003e\n\u003cli\u003eGonadal steroidogenesis and sex hormone feedback investigation\u003c\/li\u003e\n\u003cli\u003eFertility biology and gametogenesis modelling\u003c\/li\u003e\n\u003c\/ul\u003e\u003ch3\u003eSpecifications\u003c\/h3\u003e\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eMolecular Formula:\u003c\/strong\u003e C₅₅H₇N₁₇O₁₃\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eCAS Number:\u003c\/strong\u003e 33515-09-2\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003ePurity:\u003c\/strong\u003e ≥98%\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eMolecular Weight:\u003c\/strong\u003e 1182.3 g\/mol\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eForm:\u003c\/strong\u003e Lyophilised powder\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eStorage:\u003c\/strong\u003e -20°C\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eShelf Life:\u003c\/strong\u003e 24 months\u003c\/li\u003e\n\u003c\/ul\u003e\u003cp\u003e\u003cem\u003eThis product is intended for legitimate laboratory and analytical research use only. Not for diagnostic, therapeutic, or consumer use.\u003c\/em\u003e\u003c\/p\u003e","brand":"Vanta Labs","offers":[{"title":"2mg","offer_id":58103427858696,"sku":"GONADO-2MG","price":14.99,"currency_code":"GBP","in_stock":true},{"title":"5mg","offer_id":58103427891464,"sku":"GONADO-5MG","price":27.5,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1049\/8886\/8872\/files\/gonadorelin.png?v=1782941080"},{"product_id":"hcg","title":"HCG","description":"\u003ch2\u003eHCG (Human Chorionic Gonadotropin)\u003c\/h2\u003e\n\u003cp\u003eHCG (Human Chorionic Gonadotropin) is a research-grade recombinant glycoprotein hormone structurally homologous to luteinising hormone (LH), developed for preclinical investigation of gonadal steroidogenesis, Leydig cell function, and reproductive endocrinology. Endogenously produced by the syncytiotrophoblast during early pregnancy, HCG acts as a potent LH receptor agonist and is widely used in experimental models of testosterone biosynthesis, spermatogenesis, and HPG axis regulation.\u003c\/p\u003e\n\u003ch3\u003eMechanism of Action\u003c\/h3\u003e\n\u003cp\u003eHCG binds to the LH\/hCG receptor (LHCGR) on Leydig cells in the testes and theca cells in the ovary, activating adenylyl cyclase via Gs protein coupling and increasing intracellular cAMP. This triggers the StAR protein-mediated transport of cholesterol into the mitochondria and the subsequent enzymatic cascade of steroidogenesis, culminating in testosterone (in males) or oestradiol and progesterone (in females) production. HCG also supports Sertoli cell function and spermatogenesis indirectly through testosterone-mediated signalling, and has been studied for its role in luteal phase support and corpus luteum maintenance.\u003c\/p\u003e\n\u003ch3\u003eResearch Applications\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003eLeydig cell steroidogenesis and testosterone biosynthesis studies\u003c\/li\u003e\n\u003cli\u003eLH\/hCG receptor (LHCGR) signalling research\u003c\/li\u003e\n\u003cli\u003eHPG axis regulation and gonadotropin biology investigation\u003c\/li\u003e\n\u003cli\u003eSpermatogenesis and male reproductive endocrinology modelling\u003c\/li\u003e\n\u003cli\u003eOvarian function, luteal phase, and corpus luteum research\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3\u003eSpecifications\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eMolecular Formula:\u003c\/strong\u003e \u003cmeta charset=\"utf-8\"\u003eC₁₁₀₅H₁₇₇₀N₃₁₈O₃₃₆S₂₆\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eCAS Number:\u003c\/strong\u003e \u003cmeta charset=\"utf-8\"\u003e9002-61-3\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003ePurity:\u003c\/strong\u003e ≥98%\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eMolecular Weight:\u003c\/strong\u003e ~36,700 Da (glycosylated)\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eForm:\u003c\/strong\u003e Lyophilised powder\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eStorage:\u003c\/strong\u003e -20°C\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eShelf Life:\u003c\/strong\u003e 24 months\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cem\u003eThis product is intended for legitimate laboratory and analytical research use only. Not for diagnostic, therapeutic, or consumer use.\u003c\/em\u003e\u003c\/p\u003e","brand":"Vanta Labs","offers":[{"title":"1000 IU","offer_id":58103427924232,"sku":"HCG-1000IU","price":39.99,"currency_code":"GBP","in_stock":true},{"title":"2000 IU","offer_id":58103427957000,"sku":"HCG-2000IU","price":59.99,"currency_code":"GBP","in_stock":true},{"title":"5000 IU","offer_id":58103427989768,"sku":"HCG-5000IU","price":89.99,"currency_code":"GBP","in_stock":true},{"title":"10000 IU","offer_id":58103428022536,"sku":"HCG-10000IU","price":130.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1049\/8886\/8872\/files\/hcg.png?v=1782941253"},{"product_id":"hmg","title":"HMG","description":"\u003ch2\u003eHMG (Human Menopausal Gonadotropin)\u003c\/h2\u003e\u003cp\u003eHuman Menopausal Gonadotropin (HMG) is a purified gonadotropin preparation derived from the urine of postmenopausal women, containing a standardised combination of follicle-stimulating hormone (FSH) and luteinising hormone (LH) activity in an approximately 1:1 ratio, supplied at 75 IU per vial. HMG is one of the most extensively studied gonadotropin preparations in reproductive endocrinology research, with well-characterised pharmacological profiles for both FSH and LH receptor activation. It serves as a research tool for investigating gonadotropin-mediated signalling in the hypothalamic-pituitary-gonadal (HPG) axis, folliculogenesis, steroidogenesis, and spermatogenesis in preclinical models.\u003c\/p\u003e\u003ch3\u003eMechanism of Action\u003c\/h3\u003e\u003cp\u003eHMG exerts its biological effects through the combined action of its FSH and LH components, each acting on distinct G-protein-coupled receptors (GPCRs) in gonadal tissue. FSH binds to the FSH receptor (FSHR) on granulosa cells (female) and Sertoli cells (male), activating Gs-mediated adenylyl cyclase and cAMP\/PKA signalling to promote follicular development, aromatase expression, and oestrogen synthesis in females, and to support spermatogenesis and inhibin B production in males. LH binds to the LH receptor (LHR) on theca cells (female) and Leydig cells (male), stimulating androgen synthesis via the cAMP\/PKA\/StAR pathway — driving testosterone production in males and androstenedione synthesis (for aromatisation to oestradiol) in females. Together, FSH and LH activity in HMG recapitulates the endogenous gonadotropin milieu required for gonadal function, making it a valuable tool for studying HPG axis pharmacology and reproductive biology.\u003c\/p\u003e\u003ch3\u003eResearch Applications\u003c\/h3\u003e\u003cul\u003e\n\u003cli\u003eFSH receptor (FSHR) and LH receptor (LHR) pharmacology and gonadotropin signalling studies\u003c\/li\u003e\n\u003cli\u003eFolliculogenesis, granulosa cell biology, and ovarian steroidogenesis research\u003c\/li\u003e\n\u003cli\u003eSpermatogenesis, Sertoli cell function, and male reproductive biology investigation\u003c\/li\u003e\n\u003cli\u003eHPG axis regulation, gonadotropin feedback, and reproductive neuroendocrinology research\u003c\/li\u003e\n\u003cli\u003eHypogonadotrophic hypogonadism and fertility disorder preclinical models\u003c\/li\u003e\n\u003c\/ul\u003e\u003ch3\u003eSpecifications\u003c\/h3\u003e\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eMolecular Formula:\u003c\/strong\u003e Glycoprotein hormone (FSH + LH, ~1:1 ratio)\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eMolecular Weight:\u003c\/strong\u003e ~34 kDa\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eCAS Number:\u003c\/strong\u003e 9002-68-0\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003ePurity:\u003c\/strong\u003e ≥95%\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eForm:\u003c\/strong\u003e Lyophilised powder\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eStorage:\u003c\/strong\u003e -20°C\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eShelf Life:\u003c\/strong\u003e 24 months\u003c\/li\u003e\n\u003c\/ul\u003e\u003cp\u003e\u003cem\u003eThis product is intended for legitimate laboratory and analytical research use only. Not for diagnostic, therapeutic, or consumer use.\u003c\/em\u003e\u003c\/p\u003e","brand":"Vanta Labs","offers":[{"title":"75 IU","offer_id":58103428448520,"sku":"HMG-75IU","price":32.5,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1049\/8886\/8872\/files\/hmg.png?v=1782923353"},{"product_id":"kisspeptin-10","title":"Kisspeptin-10","description":"\u003ch2\u003eKisspeptin-10\u003c\/h2\u003e\n\u003cp\u003eKisspeptin-10 is a synthetic decapeptide corresponding to the C-terminal 10 amino acids of the kisspeptin family of neuropeptides, which are encoded by the KISS1 gene. Kisspeptins are endogenous ligands of the G-protein-coupled receptor GPR54 (also known as KISS1R), expressed predominantly in the hypothalamus, pituitary, and gonads. Kisspeptin-10 represents the minimal bioactive fragment of the kisspeptin family and is the most potent and widely studied isoform in reproductive neuroendocrinology research. It is a critical regulator of the hypothalamic-pituitary-gonadal (HPG) axis and has been extensively investigated in preclinical and clinical research for its roles in GnRH pulse generation, puberty onset, and fertility regulation.\u003c\/p\u003e\n\u003ch3\u003eMechanism of Action\u003c\/h3\u003e\n\u003cp\u003eKisspeptin-10 acts as a potent agonist of GPR54 (KISS1R), a Gq\/11-coupled receptor expressed on GnRH neurons in the hypothalamic arcuate nucleus (ARC) and anteroventral periventricular nucleus (AVPV). GPR54 activation stimulates phospholipase C (PLC), generating IP3 and DAG, which increase intracellular calcium and activate PKC, leading to membrane depolarisation and GnRH pulse release. GnRH then stimulates pituitary gonadotroph cells to secrete LH and FSH, which drive gonadal steroidogenesis and gametogenesis. Kisspeptin neurons in the ARC also integrate metabolic signals (leptin, insulin, ghrelin) and sex steroid feedback, making the kisspeptin-GPR54 axis a key regulatory node for reproductive function, energy balance, and pubertal timing.\u003c\/p\u003e\n\u003ch3\u003eResearch Applications\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003eGPR54\/KISS1R pharmacology and GnRH pulse generation studies\u003c\/li\u003e\n\u003cli\u003eHPG axis regulation, LH\/FSH secretion, and gonadotrophin research\u003c\/li\u003e\n\u003cli\u003ePuberty onset, reproductive neuroendocrinology, and fertility investigation\u003c\/li\u003e\n\u003cli\u003eMetabolic-reproductive axis integration and energy balance research\u003c\/li\u003e\n\u003cli\u003eHypogonadotrophic hypogonadism and fertility disorder preclinical models\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3\u003eSpecifications\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eMolecular Formula:\u003c\/strong\u003e \u003cmeta charset=\"utf-8\"\u003eC₆₃H₈₃N₁₇O₁₄\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eMolecular Weight:\u003c\/strong\u003e 1302.5 g\/mol\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eCAS Number:\u003c\/strong\u003e \u003cmeta charset=\"utf-8\"\u003e374675-21-5\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003ePurity:\u003c\/strong\u003e ≥98%\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eForm:\u003c\/strong\u003e Lyophilised powder\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eStorage:\u003c\/strong\u003e -20°C\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eShelf Life:\u003c\/strong\u003e 24 months\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cem\u003eThis product is intended for legitimate laboratory and analytical research use only. Not for diagnostic, therapeutic, or consumer use.\u003c\/em\u003e\u003c\/p\u003e","brand":"Vanta Labs","offers":[{"title":"5mg","offer_id":58103428743432,"sku":"KISS-5MG","price":19.9,"currency_code":"GBP","in_stock":true},{"title":"10mg","offer_id":58103428776200,"sku":"KISS-10MG","price":24.99,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1049\/8886\/8872\/files\/kisspeptin-10.png?v=1782920859"},{"product_id":"oxytocin","title":"Oxytocin Acetate","description":"\u003ch2\u003eOxytocin Acetate\u003c\/h2\u003e\n\u003cp\u003eOxytocin Acetate is the acetate salt form of oxytocin, a synthetic nonapeptide (Cys-Tyr-Ile-Gln-Asn-Cys-Pro-Leu-Gly-NH2) identical in sequence to the endogenous neurohypophysial hormone produced in the hypothalamus and released by the posterior pituitary. Oxytocin is one of the most extensively studied neuropeptides in biomedical research, with well-characterised roles in social behaviour, bonding, stress regulation, uterine contractility, and lactation. It is supplied here as a research-grade lyophilised compound for in vitro and preclinical investigation of oxytocin receptor pharmacology and neuroendocrine signalling.\u003c\/p\u003e\n\u003ch3\u003eMechanism of Action\u003c\/h3\u003e\n\u003cp\u003eOxytocin exerts its biological effects by binding to the oxytocin receptor (OXTR), a G-protein-coupled receptor (Gq\/11) expressed in the brain, uterus, mammary gland, heart, and immune cells. Central OXTR activation modulates dopaminergic and serotonergic neurotransmission in limbic regions, influencing social recognition, trust, anxiety, and stress responses via HPA axis modulation. Peripheral OXTR activation stimulates smooth muscle contraction in the uterus and myoepithelial cells of the mammary gland. Oxytocin also demonstrates anti-inflammatory properties through modulation of NF-κB signalling and cytokine release in immune cells.\u003c\/p\u003e\n\u003ch3\u003eResearch Applications\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003eOxytocin receptor (OXTR) pharmacology and G-protein signalling studies\u003c\/li\u003e\n\u003cli\u003eSocial behaviour, bonding, and trust neuroscience research\u003c\/li\u003e\n\u003cli\u003eHPA axis modulation and stress response investigation\u003c\/li\u003e\n\u003cli\u003eUterine contractility and smooth muscle physiology research\u003c\/li\u003e\n\u003cli\u003eNeuroimmune modulation and anti-inflammatory signalling studies\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3\u003eSpecifications\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eMolecular Formula:\u003c\/strong\u003e \u003cmeta charset=\"utf-8\"\u003eC₄₃H₆₆N₁₂O₁₂S₂ • xC₂H₄O₂\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eMolecular Weight:\u003c\/strong\u003e \u003cmeta charset=\"utf-8\"\u003e1067.24 g\/mol\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eCAS Number:\u003c\/strong\u003e \u003cmeta charset=\"utf-8\"\u003e6233-83-6\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003ePurity:\u003c\/strong\u003e ≥98%\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eForm:\u003c\/strong\u003e Lyophilised powder\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eStorage:\u003c\/strong\u003e -20°C\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eShelf Life:\u003c\/strong\u003e 24 months\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cem\u003eThis product is intended for legitimate laboratory and analytical research use only. Not for diagnostic, therapeutic, or consumer use.\u003c\/em\u003e\u003c\/p\u003e","brand":"Vanta Labs","offers":[{"title":"5mg","offer_id":58103430316296,"sku":"OXY-5MG","price":18.0,"currency_code":"GBP","in_stock":true},{"title":"10mg","offer_id":58103430349064,"sku":"OXY-10MG","price":29.9,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1049\/8886\/8872\/files\/oxytocin-acetate.png?v=1782897490"}],"url":"https:\/\/vantalabsuk.com\/collections\/hormones-fertility-peptides.oembed","provider":"Vanta Labs","version":"1.0","type":"link"}