{"title":"GLP-1 Peptides","description":"\u003cp\u003eResearch peptides studied for metabolic regulation, appetite signalling, and glucose homeostasis. Includes GLP-1 receptor agonists and dual\/triple agonists under active investigation.\u003c\/p\u003e","products":[{"product_id":"cagrilintide","title":"Cagrilintide","description":"\u003ch2\u003eCagrilintide\u003c\/h2\u003e\n\u003cp\u003eCagrilintide is a long-acting amylin analogue developed for preclinical investigation of metabolic regulation, appetite control, and body weight modulation. As a synthetic analogue of human amylin, it is designed to resist enzymatic degradation and provide sustained receptor engagement, making it a valuable tool compound for studying amylin receptor biology and its role in energy homeostasis. Cagrilintide has been investigated in combination with GLP-1 receptor agonists for its additive effects on satiety and metabolic parameters.\u003c\/p\u003e\n\u003ch3\u003eMechanism of Action\u003c\/h3\u003e\n\u003cp\u003eCagrilintide acts as an agonist at amylin receptors (AMY1, AMY2, AMY3), which are heterodimeric complexes of the calcitonin receptor and receptor activity-modifying proteins (RAMPs). Activation of these receptors in the hypothalamus and brainstem suppresses appetite, slows gastric emptying, and reduces postprandial glucagon secretion. Its extended half-life relative to native amylin is achieved through fatty acid conjugation, enabling once-weekly dosing paradigms in research models.\u003c\/p\u003e\n\u003ch3\u003eResearch Applications\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003eAmylin receptor pharmacology and signalling studies\u003c\/li\u003e\n\u003cli\u003eAppetite regulation and satiety pathway investigation\u003c\/li\u003e\n\u003cli\u003eMetabolic syndrome and obesity modelling\u003c\/li\u003e\n\u003cli\u003eCombination peptide therapy research (e.g. with GLP-1 analogues)\u003c\/li\u003e\n\u003cli\u003eGastric motility and postprandial glucagon studies\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3\u003eSpecifications\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eMolecular Formula:\u003c\/strong\u003e \u003cmeta charset=\"utf-8\"\u003eC₁₉₄H₃₁₂N₅₄O₅₉S₂\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eCAS Number:\u003c\/strong\u003e 2173044-15-8\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003ePurity:\u003c\/strong\u003e ≥98%\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eMolecular Weight:\u003c\/strong\u003e 4421.1 g\/mol\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eForm:\u003c\/strong\u003e Lyophilised powder\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eStorage:\u003c\/strong\u003e -20°C\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eShelf Life:\u003c\/strong\u003e 24 months\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cem\u003eThis product is intended for legitimate laboratory and analytical research use only. Not for diagnostic, therapeutic, or consumer use.\u003c\/em\u003e\u003c\/p\u003e","brand":"Vanta Labs","offers":[{"title":"5mg","offer_id":58103426679048,"sku":"CAGRI-5MG","price":20.99,"currency_code":"GBP","in_stock":true},{"title":"10mg","offer_id":58103426711816,"sku":"CAGRI-10MG","price":39.99,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1049\/8886\/8872\/files\/cagrilintide.png?v=1782935141"},{"product_id":"liraglutide","title":"Liraglutide","description":"\u003ch2\u003eLiraglutide\u003c\/h2\u003e\n\u003cp\u003eLiraglutide is a synthetic acylated analogue of human glucagon-like peptide-1 (GLP-1), developed by Novo Nordisk. It shares 97% sequence homology with endogenous GLP-1(7-37) and incorporates a C16 fatty acid chain attached via a glutamic acid linker to Lys26, enabling reversible albumin binding that extends its plasma half-life to approximately 13 hours — significantly longer than native GLP-1 (1–2 minutes). Liraglutide is one of the most extensively studied GLP-1 receptor agonists in metabolic research, with a well-characterised pharmacological profile across glycaemic regulation, body weight, cardiovascular function, and neuroprotection.\u003c\/p\u003e\n\u003ch3\u003eMechanism of Action\u003c\/h3\u003e\n\u003cp\u003eLiraglutide acts as a potent, selective agonist of the GLP-1 receptor (GLP-1R), a class B G-protein-coupled receptor (Gs) expressed in pancreatic β-cells, hypothalamus, brainstem, heart, kidney, and peripheral tissues. GLP-1R activation stimulates glucose-dependent insulin secretion, suppresses glucagon release, slows gastric emptying, and reduces appetite via central POMC\/CART neuron activation and vagal afferent signalling. Liraglutide also activates GLP-1R in the cardiovascular system, promoting cardioprotective effects via cAMP-mediated signalling in cardiomyocytes, and in the brain, where it modulates dopaminergic and inflammatory pathways of research interest in neurodegeneration.\u003c\/p\u003e\n\u003ch3\u003eResearch Applications\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003eGLP-1 receptor pharmacology and class B GPCR signalling studies\u003c\/li\u003e\n\u003cli\u003eGlucose-dependent insulin secretion and pancreatic β-cell function research\u003c\/li\u003e\n\u003cli\u003eAppetite regulation, hypothalamic energy homeostasis, and obesity investigation\u003c\/li\u003e\n\u003cli\u003eCardiovascular protection and cardiomyocyte GLP-1R signalling research\u003c\/li\u003e\n\u003cli\u003eNeurodegeneration, neuroinflammation, and GLP-1R neuroprotection models\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3\u003eSpecifications\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eMolecular Formula:\u003c\/strong\u003e \u003cmeta charset=\"utf-8\"\u003eC₁₇₂H₂₆₅N₄₃O₅₁\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eMolecular Weight:\u003c\/strong\u003e 3751.2 g\/mol\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eCAS Number:\u003c\/strong\u003e 204656-20-2\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003ePurity:\u003c\/strong\u003e ≥98%\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eForm:\u003c\/strong\u003e Lyophilised powder\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eStorage:\u003c\/strong\u003e -20°C\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eShelf Life:\u003c\/strong\u003e 24 months\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cem\u003eThis product is intended for legitimate laboratory and analytical research use only. Not for diagnostic, therapeutic, or consumer use.\u003c\/em\u003e\u003c\/p\u003e","brand":"Vanta Labs","offers":[{"title":"5mg","offer_id":58103429267720,"sku":"LIRA-5MG","price":79.99,"currency_code":"GBP","in_stock":true},{"title":"10mg","offer_id":58103429300488,"sku":"LIRA-10MG","price":149.99,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1049\/8886\/8872\/files\/liraglutide.png?v=1782916518"},{"product_id":"mazdutide","title":"Mazdutide","description":"\u003ch2\u003eMazdutide\u003c\/h2\u003e\n\u003cp\u003eMazdutide (IBI362) is a synthetic dual GLP-1R\/GCGR agonist peptide developed by Innovent Biologics as a next-generation metabolic research compound. It combines glucagon-like peptide-1 receptor (GLP-1R) agonism with glucagon receptor (GCGR) agonism in a single molecule, targeting complementary metabolic pathways to investigate synergistic effects on energy expenditure, hepatic lipid metabolism, and body weight regulation. Mazdutide has entered clinical research as a candidate for obesity and metabolic disease, and is supplied here as a research-grade lyophilised compound for preclinical investigation.\u003c\/p\u003e\n\u003ch3\u003eMechanism of Action\u003c\/h3\u003e\n\u003cp\u003eMazdutide simultaneously activates GLP-1R and GCGR — both G-protein-coupled receptors signalling via cAMP. GLP-1R activation enhances glucose-dependent insulin secretion, suppresses glucagon release, slows gastric emptying, and reduces appetite via hypothalamic POMC\/CART neuron activation. GCGR activation stimulates hepatic glucose output, promotes lipolysis in adipose tissue, and increases energy expenditure through thermogenic mechanisms including brown adipose tissue (BAT) activation. The dual agonism is designed to leverage the appetite-suppressing and insulinotropic effects of GLP-1R alongside the lipolytic and thermogenic effects of GCGR, producing a complementary metabolic profile of research interest in obesity and NAFLD\/NASH models.\u003c\/p\u003e\n\u003ch3\u003eResearch Applications\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003eDual GLP-1R\/GCGR pharmacology and receptor co-activation studies\u003c\/li\u003e\n\u003cli\u003eHepatic lipid metabolism, NAFLD, and NASH preclinical models\u003c\/li\u003e\n\u003cli\u003eEnergy expenditure, thermogenesis, and brown adipose tissue research\u003c\/li\u003e\n\u003cli\u003eAppetite regulation and hypothalamic energy homeostasis investigation\u003c\/li\u003e\n\u003cli\u003eObesity, body composition, and metabolic syndrome research\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3\u003eSpecifications\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eMolecular Formula:\u003c\/strong\u003e \u003cmeta charset=\"utf-8\"\u003eC₂₁₀H₃₂₂N₄₆O₆₇\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eMolecular Weight:\u003c\/strong\u003e \u003cmeta charset=\"utf-8\"\u003e4563.10 g\/mol\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eCAS Number:\u003c\/strong\u003e \u003cmeta charset=\"utf-8\"\u003e2259884-03-0\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003ePurity:\u003c\/strong\u003e ≥98%\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eForm:\u003c\/strong\u003e Lyophilised powder\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eStorage:\u003c\/strong\u003e -20°C\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eShelf Life:\u003c\/strong\u003e 24 months\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cem\u003eThis product is intended for legitimate laboratory and analytical research use only. Not for diagnostic, therapeutic, or consumer use.\u003c\/em\u003e\u003c\/p\u003e","brand":"Vanta Labs","offers":[{"title":"5mg","offer_id":58103429398792,"sku":"MAZDU-5MG","price":89.99,"currency_code":"GBP","in_stock":true},{"title":"10mg","offer_id":58103429431560,"sku":"MAZDU-10MG","price":159.99,"currency_code":"GBP","in_stock":true},{"title":"20mg","offer_id":58103429464328,"sku":"MAZDU-20MG","price":310.99,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1049\/8886\/8872\/files\/mazdutide.png?v=1782915660"},{"product_id":"retatrutide","title":"Retatrutide","description":"\u003ch2\u003eRetatrutide\u003c\/h2\u003e\n\u003cp\u003eRetatrutide is a synthetic triple agonist peptide targeting the glucagon receptor (GCGR), the glucagon-like peptide-1 receptor (GLP-1R), and the glucose-dependent insulinotropic polypeptide receptor (GIPR) — making it the first triple incretin receptor agonist to enter advanced clinical research. Developed as a next-generation metabolic research compound, retatrutide combines the complementary mechanisms of all three incretin and glucagon pathways to investigate synergistic effects on energy expenditure, appetite regulation, hepatic lipid metabolism, and body weight. It is supplied here as a lyophilised research compound for in vitro and preclinical investigation.\u003c\/p\u003e\n\u003ch3\u003eMechanism of Action\u003c\/h3\u003e\n\u003cp\u003eRetatrutide simultaneously activates GLP-1R, GIPR, and GCGR — all G-protein-coupled receptors signalling via cAMP. GLP-1R activation enhances glucose-dependent insulin secretion and suppresses appetite via hypothalamic pathways; GIPR activation provides additional insulinotropic effects and may modulate adipose tissue metabolism; GCGR activation stimulates hepatic glucose output, promotes lipolysis, and increases energy expenditure through thermogenic mechanisms. The triple agonism is hypothesised to produce additive or synergistic metabolic effects exceeding those of dual agonists, making retatrutide a key tool for studying multi-receptor incretin pharmacology and metabolic regulation.\u003c\/p\u003e\n\u003ch3\u003eResearch Applications\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003eTriple GLP-1R\/GIPR\/GCGR pharmacology and receptor crosstalk studies\u003c\/li\u003e\n\u003cli\u003eEnergy expenditure, thermogenesis, and adipose tissue metabolism research\u003c\/li\u003e\n\u003cli\u003eHepatic lipid metabolism and NAFLD\/NASH preclinical models\u003c\/li\u003e\n\u003cli\u003eAppetite regulation and hypothalamic energy homeostasis investigation\u003c\/li\u003e\n\u003cli\u003eObesity, body composition, and metabolic syndrome research\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3\u003eSpecifications\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eMolecular Formula:\u003c\/strong\u003e \u003cmeta charset=\"utf-8\"\u003eC₂₂₁H₃₄₂N₄₆O₆₈\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eMolecular Weight:\u003c\/strong\u003e 4731.4 g\/mol\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eCAS Number:\u003c\/strong\u003e 2381089-83-2\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003ePurity:\u003c\/strong\u003e ≥98%\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eForm:\u003c\/strong\u003e Lyophilised powder\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eStorage:\u003c\/strong\u003e -20°C\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eShelf Life:\u003c\/strong\u003e 24 months\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cem\u003eThis product is intended for legitimate laboratory and analytical research use only. Not for diagnostic, therapeutic, or consumer use.\u003c\/em\u003e\u003c\/p\u003e","brand":"Vanta Labs","offers":[{"title":"5mg","offer_id":58103430578440,"sku":"RETA-5MG","price":38.99,"currency_code":"GBP","in_stock":true},{"title":"10mg","offer_id":58103430611208,"sku":"RETA-10MG","price":59.99,"currency_code":"GBP","in_stock":true},{"title":"15mg","offer_id":58103430643976,"sku":"RETA-15MG","price":69.95,"currency_code":"GBP","in_stock":true},{"title":"20mg","offer_id":58103430676744,"sku":"RETA-20MG","price":79.95,"currency_code":"GBP","in_stock":true},{"title":"30mg","offer_id":58103430709512,"sku":"RETA-30MG","price":110.99,"currency_code":"GBP","in_stock":true},{"title":"40mg","offer_id":58103430742280,"sku":"RETA-40MG","price":139.99,"currency_code":"GBP","in_stock":true},{"title":"50mg","offer_id":58103430775048,"sku":"RETA-50MG","price":169.99,"currency_code":"GBP","in_stock":true},{"title":"60mg","offer_id":58103430807816,"sku":"RETA-60MG","price":189.99,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1049\/8886\/8872\/files\/retatrutide.png?v=1782895567"},{"product_id":"semaglutide","title":"Semaglutide","description":"\u003ch2\u003eSemaglutide\u003c\/h2\u003e\n\u003cp\u003eSemaglutide is a synthetic 31-amino acid GLP-1 receptor agonist peptide with 94% sequence homology to endogenous glucagon-like peptide-1 (GLP-1). It incorporates a C18 fatty diacid chain attached via a linker to lysine at position 26, enabling reversible albumin binding that dramatically extends its plasma half-life to approximately 7 days. Semaglutide is one of the most extensively studied GLP-1 receptor agonists in the research literature, with a substantial body of preclinical and clinical data supporting its investigation in metabolic disease, obesity, and cardiovascular research.\u003c\/p\u003e\n\u003ch3\u003eMechanism of Action\u003c\/h3\u003e\n\u003cp\u003eSemaglutide binds to and activates the GLP-1 receptor (GLP-1R), a G-protein-coupled receptor expressed on pancreatic beta cells, hypothalamic neurons, and peripheral tissues. GLP-1R activation stimulates glucose-dependent insulin secretion, suppresses glucagon release, slows gastric emptying, and reduces appetite via central hypothalamic pathways — particularly through activation of POMC\/CART neurons and inhibition of NPY\/AgRP neurons in the arcuate nucleus. The albumin-binding fatty acid modification confers resistance to DPP-4 degradation and renal clearance, making semaglutide a valuable long-acting tool for studying GLP-1 receptor pharmacology and metabolic regulation.\u003c\/p\u003e\n\u003ch3\u003eResearch Applications\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003eGLP-1 receptor pharmacology and incretin biology studies\u003c\/li\u003e\n\u003cli\u003eGlucose-dependent insulin secretion and pancreatic beta-cell function research\u003c\/li\u003e\n\u003cli\u003eHypothalamic appetite regulation and energy homeostasis modelling\u003c\/li\u003e\n\u003cli\u003eObesity, body weight regulation, and adipose tissue metabolism investigation\u003c\/li\u003e\n\u003cli\u003eCardiovascular and cardiometabolic disease preclinical models\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3\u003eSpecifications\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eMolecular Formula:\u003c\/strong\u003e \u003cmeta charset=\"utf-8\"\u003eC₁₈₇H₂₉₁N₄₅O₅₉\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eMolecular Weight:\u003c\/strong\u003e 4113.6 g\/mol\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eCAS Number:\u003c\/strong\u003e 910463-68-2\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003ePurity:\u003c\/strong\u003e ≥98%\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eForm:\u003c\/strong\u003e Lyophilised powder\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eStorage:\u003c\/strong\u003e -20°C\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eShelf Life:\u003c\/strong\u003e 24 months\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cem\u003eThis product is intended for legitimate laboratory and analytical research use only. Not for diagnostic, therapeutic, or consumer use.\u003c\/em\u003e\u003c\/p\u003e","brand":"Vanta Labs","offers":[{"title":"2mg","offer_id":58103430971656,"sku":"SEMA-2MG","price":11.99,"currency_code":"GBP","in_stock":true},{"title":"5mg","offer_id":58103431004424,"sku":"SEMA-5MG","price":18.99,"currency_code":"GBP","in_stock":true},{"title":"10mg","offer_id":58103431037192,"sku":"SEMA-10MG","price":28.99,"currency_code":"GBP","in_stock":true},{"title":"15mg","offer_id":58103431069960,"sku":"SEMA-15MG","price":40.99,"currency_code":"GBP","in_stock":true},{"title":"20mg","offer_id":58103431102728,"sku":"SEMA-20MG","price":58.99,"currency_code":"GBP","in_stock":true},{"title":"30mg","offer_id":58103431135496,"sku":"SEMA-30mg","price":80.99,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1049\/8886\/8872\/files\/semaglutide.png?v=1782895227"},{"product_id":"survodutide","title":"Survodutide","description":"\u003ch2\u003eSurvodutide\u003c\/h2\u003e\n\u003cp\u003eSurvodutide is a synthetic dual agonist peptide targeting both the glucagon receptor (GCGR) and the glucagon-like peptide-1 receptor (GLP-1R). It represents a next-generation approach to metabolic research beyond single-receptor GLP-1 agonism, combining the complementary metabolic actions of glucagon and GLP-1 signalling pathways. Survodutide has attracted significant preclinical and clinical research interest for its potential effects on energy expenditure, hepatic lipid metabolism, and body weight regulation.\u003c\/p\u003e\n\u003ch3\u003eMechanism of Action\u003c\/h3\u003e\n\u003cp\u003eSurvodutide co-activates GLP-1R and GCGR, both G-protein-coupled receptors that signal through cAMP elevation. GLP-1R activation enhances glucose-dependent insulin secretion and suppresses appetite via central and peripheral mechanisms, while GCGR activation stimulates hepatic glucose output, promotes lipolysis, and increases energy expenditure through thermogenic pathways. The dual agonism is hypothesised to produce additive or synergistic effects on fat oxidation and weight reduction, making survodutide a valuable tool for studying GCGR\/GLP-1R crosstalk and metabolic regulation.\u003c\/p\u003e\n\u003ch3\u003eResearch Applications\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003eDual GCGR\/GLP-1R pharmacology and receptor crosstalk studies\u003c\/li\u003e\n\u003cli\u003eHepatic lipid metabolism and non-alcoholic fatty liver disease (NAFLD) models\u003c\/li\u003e\n\u003cli\u003eEnergy expenditure and thermogenesis research\u003c\/li\u003e\n\u003cli\u003eObesity and body composition preclinical investigation\u003c\/li\u003e\n\u003cli\u003eInsulin secretion and glucose homeostasis modelling\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3\u003eSpecifications\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eMolecular Formula:\u003c\/strong\u003e \u003cmeta charset=\"utf-8\"\u003e \u003cspan class=\"T286Pc\" data-sfc-cp=\"\" data-sfc-root=\"ep\" data-sfc-cb=\"\" data-complete=\"true\" data-copy-service-computed-style='font-family: \"Google Sans\", Arial, sans-serif; font-size: 16px; font-weight: 400; margin: 0px; text-decoration: none; border-bottom: 0px rgb(230, 232, 240);'\u003eC₁₉₂H₂₈₉N₄₇O₆₁\u003c!--TgQPHd||[]--\u003e\u003c\/span\u003e\u003cspan data-copy-service-computed-style='font-family: \"Google Sans\", Arial, sans-serif; font-size: 16px; font-weight: 400; margin: 0px; text-decoration: none; border-bottom: 0px rgb(230, 232, 240);'\u003e\u003c!--TgQPHd||[]--\u003e\u003c\/span\u003e\u003c!--TgQPHd||[]--\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eMolecular Weight:\u003c\/strong\u003e \u003cmeta charset=\"utf-8\"\u003e4231.69 g\/mol\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eCAS Number:\u003c\/strong\u003e \u003cmeta charset=\"utf-8\"\u003e2805997-46-8\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003ePurity:\u003c\/strong\u003e ≥98%\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eForm:\u003c\/strong\u003e Lyophilised powder\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eStorage:\u003c\/strong\u003e -20°C\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eShelf Life:\u003c\/strong\u003e 24 months\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cem\u003eThis product is intended for legitimate laboratory and analytical research use only. Not for diagnostic, therapeutic, or consumer use.\u003c\/em\u003e\u003c\/p\u003e","brand":"Vanta Labs","offers":[{"title":"2mg","offer_id":58103431659784,"sku":"SURVO-2MG","price":32.99,"currency_code":"GBP","in_stock":true},{"title":"5mg","offer_id":58103431692552,"sku":"SURVO-5MG","price":60.99,"currency_code":"GBP","in_stock":true},{"title":"10mg","offer_id":58103431725320,"sku":"SURVO-10MG","price":89.99,"currency_code":"GBP","in_stock":true},{"title":"15mg","offer_id":58103431758088,"sku":"SURVO-15MG","price":140.99,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1049\/8886\/8872\/files\/survodutide.png?v=1782893801"},{"product_id":"tirzepatide","title":"Tirzepatide","description":"\u003ch2\u003eTirzepatide\u003c\/h2\u003e\n\u003cp\u003eTirzepatide is a synthetic 39-amino acid dual agonist peptide targeting both the glucose-dependent insulinotropic polypeptide (GIP) receptor and the glucagon-like peptide-1 (GLP-1) receptor. Originally developed as a novel approach to metabolic disease research, tirzepatide has attracted significant scientific interest for its dual incretin mechanism, which distinguishes it from single-receptor GLP-1 agonists. It is supplied here as a lyophilised research compound for in vitro and preclinical investigation.\u003c\/p\u003e\n\u003ch3\u003eMechanism of Action\u003c\/h3\u003e\n\u003cp\u003eTirzepatide acts as a co-agonist at GIP (GIPR) and GLP-1 (GLP-1R) receptors, both of which are G-protein-coupled receptors that signal via cAMP elevation. GLP-1R activation enhances glucose-dependent insulin secretion and suppresses glucagon release, while GIPR activation contributes additional insulinotropic and potentially adipose-regulatory effects. The dual agonism is hypothesised to produce synergistic metabolic effects beyond those achievable with GLP-1 monotherapy, making tirzepatide a key subject in obesity, insulin resistance, and metabolic syndrome research.\u003c\/p\u003e\n\u003ch3\u003eResearch Applications\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003eDual GIP\/GLP-1 receptor pharmacology studies\u003c\/li\u003e\n\u003cli\u003eInsulin secretion and glucose homeostasis modelling\u003c\/li\u003e\n\u003cli\u003eObesity and adipose tissue metabolism research\u003c\/li\u003e\n\u003cli\u003eIncretin biology and pancreatic beta-cell function investigation\u003c\/li\u003e\n\u003cli\u003eMetabolic syndrome and insulin resistance preclinical models\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3\u003eSpecifications\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eMolecular Formula:\u003c\/strong\u003e \u003cmeta charset=\"utf-8\"\u003eC₂₂₅H₃₄₈N₄₈O₆₈\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eMolecular Weight:\u003c\/strong\u003e 4813.5 g\/mol\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eCAS Number:\u003c\/strong\u003e 2023788-19-2\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003ePurity:\u003c\/strong\u003e ≥98%\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eForm:\u003c\/strong\u003e Lyophilised powder\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eStorage:\u003c\/strong\u003e -20°C\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eShelf Life:\u003c\/strong\u003e 24 months\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cem\u003eThis product is intended for legitimate laboratory and analytical research use only. Not for diagnostic, therapeutic, or consumer use.\u003c\/em\u003e\u003c\/p\u003e","brand":"Vanta Labs","offers":[{"title":"5mg","offer_id":58103432380680,"sku":"TIRZE-5MG","price":21.99,"currency_code":"GBP","in_stock":true},{"title":"10mg","offer_id":58103432413448,"sku":"TIRZE-10MG","price":44.99,"currency_code":"GBP","in_stock":true},{"title":"15mg","offer_id":58103432446216,"sku":"TIRZE-15MG","price":55.99,"currency_code":"GBP","in_stock":true},{"title":"20mg","offer_id":58103432478984,"sku":"TIRZE-20MG","price":63.99,"currency_code":"GBP","in_stock":true},{"title":"30mg","offer_id":58103432511752,"sku":"TIRZE-30MG","price":80.99,"currency_code":"GBP","in_stock":true},{"title":"40mg","offer_id":58103432544520,"sku":"TIRZE-40MG","price":99.99,"currency_code":"GBP","in_stock":true},{"title":"60mg","offer_id":58103432577288,"sku":"TIRZE-60MG","price":139.99,"currency_code":"GBP","in_stock":true},{"title":"90mg","offer_id":58103432610056,"sku":"TIRZE-90MG","price":159.99,"currency_code":"GBP","in_stock":true},{"title":"100mg","offer_id":58103432642824,"sku":"TIRZE-100MG","price":199.99,"currency_code":"GBP","in_stock":true},{"title":"120mg","offer_id":58103432675592,"sku":"TIRZE-120MG","price":230.99,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1049\/8886\/8872\/files\/tirzepatide.png?v=1782892821"}],"url":"https:\/\/vantalabsuk.com\/collections\/glp-1-peptides.oembed","provider":"Vanta Labs","version":"1.0","type":"link"}